UniProt Q8RMD4
Acarbose 7(IV)-phosphotransferase (Q8RMD4)
Acarbose 7(IV)-phosphotransferase (UniProt Q8RMD4), EC 2.7.1.187: 2 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 11 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- Q8RMD4
- Protein
- Acarbose 7(IV)-phosphotransferase
- EC
- 2.7.1.187
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 11 · 1 record with a druggable one
Structures
3 records of Q8RMD4 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6WB7 | Acarbose Kinase AcbK as a Complex with Acarbose and AMP-PNP | x-ray diffraction | A, B, C, D | GLC, AC1, ANP, MN, NA | 11 (best 0.77) |
| 6WB7 | Acarbose kinase acbk as a complex with acarbose and AMP-pnp | x-ray diffraction | A, B, C, D | GLC, AC1, ANP, MN, NA | — |
| Q8RMD4 | AlphaFold monomer V2.0 prediction for acarbose 7(IV)-phosphotransferase (Q8RMD4) | predicted | A | — | — |
Ligands
- AC1 · 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose · in 2 records
- ANP · Phosphoaminophosphonic acid-adenylate ester · in 2 records
- GLC · alpha-D-glucopyranose · in 2 records
- MN · Manganese (II) ion · in 2 records
- NA · Sodium ion · in 2 records
Experiment against prediction
- 6WB7 chain D against the predicted model Q8RMD4: TM-score 0.98, RMSD 0.92 Å
- 6WB7 chain D against the predicted model Q8RMD4: TM-score 0.98, RMSD 0.92 Å
- 6WB7 chain C against the predicted model Q8RMD4: TM-score 0.97, RMSD 1.04 Å
- 6WB7 chain C against the predicted model Q8RMD4: TM-score 0.97, RMSD 1.04 Å
- 6WB7 chain B against the predicted model Q8RMD4: TM-score 0.97, RMSD 1.17 Å
- 6WB7 chain B against the predicted model Q8RMD4: TM-score 0.97, RMSD 1.17 Å
- 6WB7 chain A against the predicted model Q8RMD4: TM-score 0.96, RMSD 1.30 Å
- 6WB7 chain A against the predicted model Q8RMD4: TM-score 0.96, RMSD 1.30 Å
Elsewhere
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