UniProt Q8R502
Volume-regulated anion channel subunit LRRC8C (Q8R502)
Volume-regulated anion channel subunit LRRC8C (UniProt Q8R502): 17 experimental structures on GenesisL1, 1 ligand bound, 118 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q8R502
- Protein
- Volume-regulated anion channel subunit LRRC8C
- Experimental structures
- 17
- Predicted models
- 0
- Ligands
- 1
- Pockets
- 118 · 16 records with a druggable one
Structures
17 records of Q8R502 in the MolNFT archive: 17 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8B40 | Structure of homomeric LRRC8C Volume-Regulated Anion Channel | electron microscopy | A, B, C, D, E, F, G | — | 20 (best 0.79) |
| 8B41 | Structure of heteromeric LRRC8A/C (1:1 co-transfected) Volume-Regulated Anion Channel in complex… | electron microscopy | E, F | — | 7 (best 0.75) |
| 8B42 | Structure of heteromeric LRRC8A/C Volume-Regulated Anion Channel. | electron microscopy | E, F | — | 7 (best 0.78) |
| 8BEN | LRR domain Structure of the LRRC8C protein | x-ray diffraction | A, B, C, D | — | 13 (best 0.82) |
| 8DR8 | LRRC8A:C conformation 2 (oblong) top mask | electron microscopy | F | PEE | 6 (best 0.80) |
| 8DRK | LRRC8A:C conformation 1 (round) top focus | electron microscopy | F | PEE | 7 (best 0.85) |
| 8DRN | LRRC8A:C conformation 1 (round) LRR focus 1 | electron microscopy | F | — | 5 (best 0.74) |
| 8DS3 | LRRC8A:C conformation 1 (round) | electron microscopy | F | PEE | 6 (best 0.85) |
| 8DS9 | LRRC8A:C in MSPE3D1 nanodisc top focus | electron microscopy | F | PEE | 5 (best 0.84) |
| 8DSA | LRRC8A:C in MSP1E3D1 nanodisc | electron microscopy | F | PEE | 5 (best 0.84) |
| 8F74 | LRRC8A(T48D):C conformation 2 top focus | electron microscopy | F | PEE | 7 (best 0.81) |
| 8F75 | LRRC8A(T48D):C conformation 2 LRR focus | electron microscopy | F | — | 4 (best 0.70) |
| 8F77 | LRRC8A(T48D):C conformation 2 top focus | electron microscopy | F | PEE | 9 (best 0.77) |
| 8F79 | LRRC8A(T48D):C conformation 2 top focus | electron microscopy | F | PEE | 6 (best 0.72) |
| 8F7B | LRRC8A(T48D):C conformation 2 top focus | electron microscopy | F | PEE | 7 (best 0.81) |
| 8F7D | LRRC8A(T48D):C conformation 2 top focus | electron microscopy | F | — | 4 (best 0.71) |
| Q8R502 | AlphaFold monomer V2.0 prediction for volume-regulated anion channel subunit LRRC8C (Q8R502) | — | — | — |
Ligands
- PEE · 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine · in 9 records
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.