UniProt Q8R0W1
CLOCK-interacting pacemaker (Q8R0W1)
CLOCK-interacting pacemaker (UniProt Q8R0W1): 4 experimental structures and 1 predicted model on GenesisL1, 22 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8R0W1
- Protein
- CLOCK-interacting pacemaker
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 22 · 2 records with a druggable one
Structures
5 records of Q8R0W1 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5VJI | Crystal structure of the CLOCK Transcription Domain Exon19 in Complex with a Repressor | x-ray diffraction | C, F | — | 4 (best 0.67) |
| 5VJI | Crystal structure of the clock transcription domain EXON19 in complex with a repressor | x-ray diffraction | C, F | — | — |
| 5VJX | Crystal structure of the CLOCK Transcription Domain Exon19 in Complex with a Repressor | x-ray diffraction | A, D, G, J, M, R, U, X, a, d | — | 18 (best 0.82) |
| 5VJX | Crystal structure of the clock transcription domain EXON19 in complex with a repressor | x-ray diffraction | A, D, G, J, M, R, U, X, a, d | — | — |
| Q8R0W1 | AlphaFold monomer V2.0 prediction for clock-interacting pacemaker (Q8R0W1) | predicted | A | — | — |
Experiment against prediction
- 5VJX chain a against the predicted model Q8R0W1: TM-score 0.94, RMSD 0.61 Å
- 5VJX chain a against the predicted model Q8R0W1: TM-score 0.94, RMSD 0.61 Å
- 5VJX chain d against the predicted model Q8R0W1: TM-score 0.94, RMSD 0.70 Å
- 5VJX chain d against the predicted model Q8R0W1: TM-score 0.94, RMSD 0.70 Å
- 5VJI chain F against the predicted model Q8R0W1: TM-score 0.89, RMSD 1.06 Å
- 5VJI chain F against the predicted model Q8R0W1: TM-score 0.89, RMSD 1.06 Å
- 5VJX chain M against the predicted model Q8R0W1: TM-score 0.88, RMSD 1.21 Å
- 5VJX chain M against the predicted model Q8R0W1: TM-score 0.88, RMSD 1.21 Å
- 5VJI chain C against the predicted model Q8R0W1: TM-score 0.88, RMSD 1.06 Å
- 5VJI chain C against the predicted model Q8R0W1: TM-score 0.88, RMSD 1.06 Å
Elsewhere
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