UniProt Q8PUB7
Type II DNA topoisomerase VI subunit A (Q8PUB7)
Type II DNA topoisomerase VI subunit A (UniProt Q8PUB7), EC 5.99.1.3: 2 experimental structures and 1 predicted model on GenesisL1, 22 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8PUB7
- Protein
- Type II DNA topoisomerase VI subunit A
- EC
- 5.99.1.3
- Experimental structures
- 2
- Predicted models
- 1
- Pockets
- 22 · 3 records with a druggable one
Structures
3 records of Q8PUB7 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2Q2E | Crystal structure of the topoisomerase VI holoenzyme from Methanosarcina mazei | x-ray diffraction | A | — | 9 (best 0.74) |
| 2Q2E | Crystal structure of the topoisomerase VI holoenzyme from methanosarcina mazei | x-ray diffraction | A | — | 9 (best 0.74) |
| Q8PUB7 | AlphaFold monomer V2.0 prediction for type 2 DNA topoisomerase 6 subunit a (Q8PUB7) | predicted | A | — | 4 (best 0.57) |
Experiment against prediction
- 2Q2E chain A against the predicted model Q8PUB7: TM-score 0.96, RMSD 1.39 Å
- 2Q2E chain A against the predicted model Q8PUB7: TM-score 0.96, RMSD 1.39 Å
Elsewhere
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