UniProt Q8NVG0
Type II pantothenate kinase (Q8NVG0)
Type II pantothenate kinase (UniProt Q8NVG0), EC 2.7.1.33: 8 experimental structures and 1 predicted model on GenesisL1, 8 ligands bound, 16 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q8NVG0
- Protein
- Type II pantothenate kinase
- EC
- 2.7.1.33
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 8
- Pockets
- 16 · 8 records with a druggable one
Structures
9 records of Q8NVG0 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4M7X | Staphylococcus aureus Type II pantothenate kinase in complex with a pantothenate analog | x-ray diffraction | A | ADP, MG, UNX, 27Q | 2 (best 0.62) |
| 4M7X | Staphylococcus aureus type II pantothenate kinase in complex with a pantothenate analog | x-ray diffraction | A | ADP, MG, UNX, 27Q | 2 (best 0.62) |
| 4M7Y | Staphylococcus aureus Type II pantothenate kinase in complex with a pantothenate analog | x-ray diffraction | A, B | 2GH, ADP, PO4, UNX | 2 (best 0.78) |
| 4M7Y | Staphylococcus aureus type II pantothenate kinase in complex with a pantothenate analog | x-ray diffraction | A, B | 2GH, ADP, PO4, UNX | 2 (best 0.78) |
| 5ELZ | Staphylococcus aureus Type II pantothenate kinase in complex with a pantothenate analog | x-ray diffraction | A | ADP, MG, 3V9, UNX | 2 (best 0.64) |
| 5ELZ | Staphylococcus aureus type II pantothenate kinase in complex with a pantothenate analog | x-ray diffraction | A | ADP, MG, 3V9, UNX | 2 (best 0.64) |
| 5JIC | Staphylococcus aureus Type II pantothenate kinase in complex with a pantothenate analog | x-ray diffraction | A | MG, ADP, N7E | 2 (best 0.63) |
| 5JIC | Staphylococcus aureus type II pantothenate kinase in complex with a pantothenate analog | x-ray diffraction | A | MG, ADP, N7E | 2 (best 0.63) |
| Q8NVG0 | AlphaFold monomer V2.0 prediction for type II pantothenate kinase (Q8NVG0) | predicted | A | — | — |
Ligands
- ADP · Adenosine-5'-diphosphate · in 8 records
- MG · Magnesium ion · in 6 records
- UNX · Unknown atom or ion · in 6 records
- 27Q · N-heptyl-N~3~-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alaninamide · in 2 records
- 2GH · N~3~-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-N-pentyl-beta-alaninamide · in 2 records
- 3V9 · N-(1,3-benzodioxol-5-ylmethyl)-N~3~-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alaninamide · in 2 records
- N7E · N~3~-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy) butanoyl]-N-(5-methoxypentyl)-beta-alaninamide · in 2 records
- PO4 · Phosphate ion · in 2 records
Experiment against prediction
- 4M7Y chain A against the predicted model Q8NVG0: TM-score 0.98, RMSD 0.81 Å
- 4M7Y chain A against the predicted model Q8NVG0: TM-score 0.98, RMSD 0.81 Å
- 4M7X chain A against the predicted model Q8NVG0: TM-score 0.96, RMSD 0.92 Å
- 4M7X chain A against the predicted model Q8NVG0: TM-score 0.96, RMSD 0.92 Å
- 4M7Y chain B against the predicted model Q8NVG0: TM-score 0.98, RMSD 0.93 Å
- 4M7Y chain B against the predicted model Q8NVG0: TM-score 0.98, RMSD 0.93 Å
- 5ELZ chain A against the predicted model Q8NVG0: TM-score 0.96, RMSD 0.92 Å
- 5ELZ chain A against the predicted model Q8NVG0: TM-score 0.96, RMSD 0.92 Å
- 5JIC chain A against the predicted model Q8NVG0: TM-score 0.96, RMSD 0.90 Å
- 5JIC chain A against the predicted model Q8NVG0: TM-score 0.96, RMSD 0.90 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.