UniProt Q8NI77
Kinesin-like protein KIF18A (Q8NI77)
Kinesin-like protein KIF18A (UniProt Q8NI77): 10 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 52 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8NI77
- Protein
- Kinesin-like protein KIF18A
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 52 · 7 records with a druggable one
Structures
11 records of Q8NI77 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3LRE | Crystal Structure Analysis of Human Kinesin-8 Motor Domain | x-ray diffraction | A, B | MG, ADP | 7 (best 0.49) |
| 3LRE | Crystal structure analysis of human kinesin-8 motor domain | x-ray diffraction | A, B | MG, ADP | 7 (best 0.49) |
| 5OAM | Molecular basis of human kinesin-8 function and inhibition | electron microscopy | K | — | 6 (best 0.59) |
| 5OAM | Molecular basis of human kinesin-8 function and inhibition | electron microscopy | K | — | 6 (best 0.59) |
| 5OCU | Molecular basis of human kinesin-8 function and inhibition | electron microscopy | K | MG, ANP | 2 (best 0.68) |
| 5OCU | Molecular basis of human kinesin-8 function and inhibition | electron microscopy | K | MG, ANP | 2 (best 0.68) |
| 5OGC | Molecular basis of human kinesin-8 function and inhibition | electron microscopy | K | 9V5 | 7 (best 0.80) |
| 5OGC | Molecular basis of human kinesin-8 function and inhibition | electron microscopy | K | 9V5 | 7 (best 0.80) |
| 7RSI | The cryo-EM map of KIF18A bound to KIFBP | electron microscopy | C | MG, ADP | 8 (best 0.72) |
| 7RSI | The cryo-EM MAP of KIF18A bound to kifbp | electron microscopy | C | MG, ADP | — |
| Q8NI77 | AlphaFold monomer V2.0 prediction for kinesin-like protein KIF18A (Q8NI77) | predicted | A | — | — |
Ligands
Experiment against prediction
- 3LRE chain A against the predicted model Q8NI77: TM-score 0.94, RMSD 1.87 Å
- 3LRE chain A against the predicted model Q8NI77: TM-score 0.94, RMSD 1.87 Å
- 3LRE chain B against the predicted model Q8NI77: TM-score 0.93, RMSD 2.11 Å
- 3LRE chain B against the predicted model Q8NI77: TM-score 0.93, RMSD 2.11 Å
- 5OCU chain K against the predicted model Q8NI77: TM-score 0.91, RMSD 2.24 Å
- 5OCU chain K against the predicted model Q8NI77: TM-score 0.91, RMSD 2.24 Å
- 5OGC chain K against the predicted model Q8NI77: TM-score 0.89, RMSD 2.67 Å
- 5OGC chain K against the predicted model Q8NI77: TM-score 0.89, RMSD 2.67 Å
- 5OAM chain K against the predicted model Q8NI77: TM-score 0.88, RMSD 2.72 Å
- 5OAM chain K against the predicted model Q8NI77: TM-score 0.88, RMSD 2.72 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.