UniProt Q8NI60
Atypical kinase COQ8A, mitochondrial (Q8NI60)
Atypical kinase COQ8A, mitochondrial (UniProt Q8NI60), EC 2.7.-.-: 6 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 10 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q8NI60
- Protein
- Atypical kinase COQ8A, mitochondrial
- EC
- 2.7.-.-
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 10 · 2 records with a druggable one
Structures
7 records of Q8NI60 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4PED | Mitochondrial ADCK3 employs an atypical protein kinase-like fold to enable coenzyme Q biosynthes | x-ray diffraction | A | — | — |
| 4PED | Mitochondrial ADCK3 employs an atypical protein kinase-like fold to enable coenzyme Q biosynthes | x-ray diffraction | A | — | — |
| 5I35 | Structure of the Human mitochondrial kinase COQ8A R611K with AMPPNP (Cerebellar Ataxia and Ubiqui… | x-ray diffraction | A | ANP | — |
| 5I35 | Structure of the human mitochondrial kinase COQ8A R611K with amppnp (cerebellar ataxia and… | x-ray diffraction | A | — | — |
| 7UDP | Crystal structure of COQ8A-CA157 inhibitor complex in space group C2 | x-ray diffraction | A | MVS | 2 (best 0.82) |
| 7UDQ | Crystal structure of COQ8A-CA157 inhibitor complex in space group P1 | x-ray diffraction | A, B | MVS, NA | 8 (best 0.84) |
| Q8NI60 | AlphaFold monomer V2.0 prediction for atypical kinase COQ8A, mitochondrial (Q8NI60) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7UDP chain A against the predicted model Q8NI60: TM-score 0.97, RMSD 1.46 Å
- 7UDQ chain B against the predicted model Q8NI60: TM-score 0.95, RMSD 1.78 Å
- 5I35 chain A against the predicted model Q8NI60: TM-score 0.95, RMSD 1.94 Å
- 5I35 chain A against the predicted model Q8NI60: TM-score 0.95, RMSD 1.94 Å
- 7UDQ chain A against the predicted model Q8NI60: TM-score 0.93, RMSD 2.12 Å
- 4PED chain A against the predicted model Q8NI60: TM-score 0.91, RMSD 2.48 Å
- 4PED chain A against the predicted model Q8NI60: TM-score 0.91, RMSD 2.48 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.