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UniProt Q8NHX9

Two pore calcium channel protein 2 (Q8NHX9)

Two pore calcium channel protein 2 (UniProt Q8NHX9): 5 experimental structures on GenesisL1, 1 ligand bound, 20 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
Q8NHX9
Protein
Two pore calcium channel protein 2
Experimental structures
5
Predicted models
0
Ligands
1
Pockets
20 · 1 record with a druggable one

Structures

5 records of Q8NHX9 in the MolNFT archive: 5 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
6NQ0Cryo-EM structure of human TPC2 channel in the ligand-bound open stateelectron microscopyA, BEUJ20 (best 0.84)
6NQ0Cryo-EM structure of human TPC2 channel in the ligand-bound open stateelectron microscopyA, BEUJ—
6NQ1Cryo-EM structure of human TPC2 channel in the apo stateelectron microscopyA, B——
6NQ2Cryo-EM structure of human TPC2 channel in the ligand-bound closed stateelectron microscopyA, BEUJ—
Q8NHX9AlphaFold monomer V2.0 prediction for two pore calcium channel protein 2 (Q8NHX9)———

Ligands

  • EUJ · (2R)-3-{[(S)-hydroxy{[(1s,2r,3r,4s,5s,6r)-2,4,6-trihydroxy-3,5-bis(phosphonooxy) cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctanoate · in 3 records

Elsewhere

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