UniProt Q8NG68
Tubulin--tyrosine ligase (Q8NG68)
Tubulin--tyrosine ligase (UniProt Q8NG68), EC 6.3.2.25: 1 experimental structure and 1 predicted model on GenesisL1, 1 ligand bound, 18 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8NG68
- Protein
- Tubulin--tyrosine ligase
- EC
- 6.3.2.25
- Experimental structures
- 1
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 18 · 2 records with a druggable one
Structures
2 records of Q8NG68 in the MolNFT archive: 1 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8ASN | Crystal structure of the apo human TTL in complex with tubulin-stathmin | x-ray diffraction | F, G, H, I | ACP | 14 (best 0.82) |
| Q8NG68 | AlphaFold monomer V2.0 prediction for tubulin--tyrosine ligase (Q8NG68) | predicted | A | — | 4 (best 0.73) |
Ligands
- ACP · Phosphomethylphosphonic acid adenylate ester · in 1 record
Experiment against prediction
- 8ASN chain F against the predicted model Q8NG68: TM-score 0.98, RMSD 0.50 Å
- 8ASN chain G against the predicted model Q8NG68: TM-score 0.98, RMSD 0.56 Å
- 8ASN chain I against the predicted model Q8NG68: TM-score 0.98, RMSD 0.50 Å
- 8ASN chain H against the predicted model Q8NG68: TM-score 0.98, RMSD 0.68 Å
Elsewhere
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