UniProt Q8NG31
Kinetochore scaffold 1 (Q8NG31)
Kinetochore scaffold 1 (UniProt Q8NG31): 10 experimental structures and 1 predicted model on GenesisL1, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8NG31
- Protein
- Kinetochore scaffold 1
- Experimental structures
- 10
- Predicted models
- 1
- Pockets
- 3 · 0 records with a druggable one
Structures
11 records of Q8NG31 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3SI5 | Kinetochore-BUBR1 kinase complex | x-ray diffraction | X, Y | — | — |
| 3SI5 | Kinetochore-BUBR1 kinase complex | x-ray diffraction | X, Y | — | — |
| 4A1G | The crystal structure of the human Bub1 TPR domain in complex with the KI motif of Knl1 | x-ray diffraction | E, F, G, H | — | — |
| 4A1G | The crystal structure of the human BUB1 tpr domain in complex with the ki motif of KNL1 | x-ray diffraction | E, F, G, H | — | — |
| 4NF9 | Structure of the Knl1/Nsl1 complex | x-ray diffraction | A, B | — | — |
| 4NF9 | Structure of the KNL1/NSL1 complex | x-ray diffraction | A, B | — | — |
| 4NFA | Structure of the C-terminal doamin of Knl1 | x-ray diffraction | A | — | — |
| 4NFA | Structure of the C-terminal doamin of KNL1 | x-ray diffraction | A | — | — |
| 8PPR | Structure of the human outer kinetochore KMN network complex | electron microscopy | K | — | 1 (best 0.48) |
| 8Q5H | Human KMN network (outer kinetochore) | electron microscopy | K | — | 2 (best 0.35) |
| Q8NG31 | AlphaFold monomer V2.0 prediction for kinetochore scaffold 1 (Q8NG31) | predicted | A | — | — |
Experiment against prediction
- 4NF9 chain B against the predicted model Q8NG31: TM-score 0.96, RMSD 1.38 Å
- 4NF9 chain B against the predicted model Q8NG31: TM-score 0.96, RMSD 1.38 Å
- 4NF9 chain A against the predicted model Q8NG31: TM-score 0.92, RMSD 1.82 Å
- 4NF9 chain A against the predicted model Q8NG31: TM-score 0.92, RMSD 1.82 Å
- 8Q5H chain K against the predicted model Q8NG31: TM-score 0.90, RMSD 2.20 Å
- 4NFA chain A against the predicted model Q8NG31: TM-score 0.83, RMSD 2.50 Å
- 4NFA chain A against the predicted model Q8NG31: TM-score 0.83, RMSD 2.50 Å
- 8PPR chain K against the predicted model Q8NG31: TM-score 0.83, RMSD 2.87 Å
- 3SI5 chain Y against the predicted model Q8NG31: TM-score 0.67, RMSD 1.21 Å
- 3SI5 chain Y against the predicted model Q8NG31: TM-score 0.67, RMSD 1.21 Å
Elsewhere
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