UniProt Q8NFU7
Methylcytosine dioxygenase TET1 (Q8NFU7)
Methylcytosine dioxygenase TET1 (UniProt Q8NFU7), EC 1.14.11.-: 2 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 12 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- Q8NFU7
- Protein
- Methylcytosine dioxygenase TET1
- EC
- 1.14.11.-
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 12 · 1 record with a druggable one
Structures
3 records of Q8NFU7 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6ASD | Zinc finger region of human TET1 in complex with CpG DNA | x-ray diffraction | C | UNX, ZN | 3 (best 0.45) |
| 6ASD | Zinc finger region of human TET1 in complex with cpg DNA | x-ray diffraction | C | UNX, ZN | — |
| Q8NFU7 | AlphaFold monomer V2.0 prediction for methylcytosine dioxygenase TET1 (Q8NFU7) | predicted | A | — | 9 (best 0.73) |
Ligands
Experiment against prediction
- 6ASD chain C against the predicted model Q8NFU7: TM-score 0.84, RMSD 1.08 Å
- 6ASD chain C against the predicted model Q8NFU7: TM-score 0.84, RMSD 1.08 Å
Elsewhere
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