UniProt Q8NEZ5
F-box only protein 22 (Q8NEZ5)
F-box only protein 22 (UniProt Q8NEZ5): 4 experimental structures and 1 predicted model on GenesisL1, 21 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8NEZ5
- Protein
- F-box only protein 22
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 21 · 3 records with a druggable one
Structures
5 records of Q8NEZ5 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8S7D | Cryo-EM structure of SKP1-FBXO22 in complex with a BACH1 BTB dimer at 3.2A resolution | electron microscopy | D | — | 4 (best 0.54) |
| 8S7E | Cryo-EM structure of SKP1-FBXO22 | electron microscopy | B | — | 3 (best 0.59) |
| 8UA3 | Cryo-EM Structure of FBOX22-BACH1BTB | electron microscopy | C | — | 3 (best 0.40) |
| 8UA6 | Cryo-EM Structure of SCF-FBOX22-BACH1BTB | electron microscopy | C | — | 11 (best 0.59) |
| Q8NEZ5 | AlphaFold monomer V2.0 prediction for F-box only protein 22 (Q8NEZ5) | predicted | A | — | — |
Experiment against prediction
- 8S7D chain D against the predicted model Q8NEZ5: TM-score 0.97, RMSD 1.27 Å
- 8UA6 chain C against the predicted model Q8NEZ5: TM-score 0.97, RMSD 1.43 Å
- 8UA3 chain C against the predicted model Q8NEZ5: TM-score 0.97, RMSD 1.36 Å
- 8S7E chain B against the predicted model Q8NEZ5: TM-score 0.96, RMSD 1.41 Å
Elsewhere
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