UniProt Q8NCN4
Peptide from E3 ubiquitin-protein ligase RNF169 (Q8NCN4)
Peptide from E3 ubiquitin-protein ligase RNF169 (UniProt Q8NCN4), EC 2.3.2.27, 6.3.2.-: 4 experimental structures and 1 predicted model on GenesisL1, 8 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q8NCN4
- Protein
- Peptide from E3 ubiquitin-protein ligase RNF169
- EC
- 2.3.2.27, 6.3.2.-
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 8 · 3 records with a druggable one
Structures
5 records of Q8NCN4 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5GG4 | Crystal structure of USP7 with RNF169 peptide | x-ray diffraction | E, F, G, H | — | 3 (best 0.82) |
| 5GG4 | Crystal structure of USP7 with RNF169 peptide | x-ray diffraction | E, F, G, H | — | — |
| 5VEY | Solution NMR structure of histone H2A-H2B mono-ubiquitylated at H2A Lys15 in complex with RNF169… | solution nmr | C | — | 2 (best 0.51) |
| 5VEY | Solution NMR structure of histone H2A-H2B mono-ubiquitylated at H2A LYS15 in complex with RNF169… | solution nmr | C | — | — |
| Q8NCN4 | AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase RNF169 (Q8NCN4) | predicted | A | — | 3 (best 0.51) |
Experiment against prediction
- 5VEY chain C against the predicted model Q8NCN4: TM-score 0.55, RMSD 2.65 Å
- 5VEY chain C against the predicted model Q8NCN4: TM-score 0.55, RMSD 2.65 Å
- 5GG4 chain G against the predicted model Q8NCN4: TM-score 0.44, RMSD 2.63 Å
- 5GG4 chain G against the predicted model Q8NCN4: TM-score 0.44, RMSD 2.63 Å
- 5GG4 chain F against the predicted model Q8NCN4: TM-score 0.37, RMSD 0.94 Å
- 5GG4 chain F against the predicted model Q8NCN4: TM-score 0.37, RMSD 0.94 Å
- 5GG4 chain E against the predicted model Q8NCN4: TM-score 0.31, RMSD 1.74 Å
- 5GG4 chain E against the predicted model Q8NCN4: TM-score 0.31, RMSD 1.74 Å
- 5GG4 chain H against the predicted model Q8NCN4: TM-score 0.29, RMSD 1.56 Å
- 5GG4 chain H against the predicted model Q8NCN4: TM-score 0.29, RMSD 1.56 Å
Elsewhere
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