UniProt Q8NC51
SERPINE1 mRNA-binding protein 1 (Q8NC51)
SERPINE1 mRNA-binding protein 1 (UniProt Q8NC51): 9 experimental structures and 1 predicted model on GenesisL1, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8NC51
- Protein
- SERPINE1 mRNA-binding protein 1
- Experimental structures
- 9
- Predicted models
- 1
- Pockets
- 1 · 1 record with a druggable one
Structures
10 records of Q8NC51 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4V6X | Structure of the human 80S ribosome | electron microscopy | Ah | — | — |
| 6Z6M | Cryo-EM structure of human 80S ribosomes bound to EBP1, eEF2 and SERBP1 | electron microscopy | CD | — | — |
| 6Z6N | Cryo-EM structure of human EBP1-80S ribosomes (focus on EBP1) | electron microscopy | CD | — | — |
| 8K2C | Cryo-EM structure of the human 80S ribosome with Tigecycline | electron microscopy | CB | — | — |
| 8XSX | Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA, SERBP1 and eEF2 | electron microscopy | CD | — | — |
| 8XSY | Cryo-EM structure of the human 80S ribosome with Tigecycline, e-tRNA and CCDC124 (40S head… | electron microscopy | CB | — | 1 (best 0.87) |
| 8XSZ | Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA and P-tRNA | electron microscopy | CB | — | — |
| 8Y0W | dormant ribosome with eIF5A, eEF2 and SERBP1 | electron microscopy | S | — | — |
| 8Y0X | Dormant ribosome with SERBP1 | electron microscopy | S | — | — |
| Q8NC51 | AlphaFold monomer V2.0 prediction for plasminogen activator inhibitor 1 RNA-binding protein (Q8NC51) | predicted | A | — | — |
Experiment against prediction
- 6Z6N chain CD against the predicted model Q8NC51: TM-score 0.34, RMSD 3.02 Å
- 8XSZ chain CB against the predicted model Q8NC51: TM-score 0.30, RMSD 0.96 Å
- 6Z6M chain CD against the predicted model Q8NC51: TM-score 0.29, RMSD 3.08 Å
- 8XSX chain CD against the predicted model Q8NC51: TM-score 0.29, RMSD 3.12 Å
- 8Y0W chain S against the predicted model Q8NC51: TM-score 0.29, RMSD 3.19 Å
- 8Y0X chain S against the predicted model Q8NC51: TM-score 0.28, RMSD 3.39 Å
- 8XSY chain CB against the predicted model Q8NC51: TM-score 0.28, RMSD 1.14 Å
- 4V6X chain Ah against the predicted model Q8NC51: TM-score 0.27, RMSD 4.47 Å
- 8K2C chain CB against the predicted model Q8NC51: TM-score 0.27, RMSD 1.22 Å
Elsewhere
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