UniProt Q8N998
Coiled-coil domain-containing protein 89 (Q8N998)
Coiled-coil domain-containing protein 89 (UniProt Q8N998): 4 experimental structures and 1 predicted model on GenesisL1, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8N998
- Protein
- Coiled-coil domain-containing protein 89
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 6 · 3 records with a druggable one
Structures
5 records of Q8N998 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8WQA | Cryo-EM structure of CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CCDC89 (conformation 1) | electron microscopy | K, L | — | 3 (best 0.76) |
| 8WQB | Cryo-EM structure of CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CCDC89 (conformation 2) | electron microscopy | K | — | 2 (best 0.54) |
| 8WQD | Local refinement of FEM1B bound with the C-degron of CCC89 | electron microscopy | G | — | 1 (best 0.53) |
| 8WQH | cryo-EM structure of neddylated CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CCDC89… | electron microscopy | G, L | — | — |
| Q8N998 | AlphaFold monomer V2.0 prediction for coiled-coil domain-containing protein 89 (Q8N998) | predicted | A | — | — |
Experiment against prediction
- 8WQH chain G against the predicted model Q8N998: TM-score 0.70, RMSD 0.66 Å
- 8WQH chain L against the predicted model Q8N998: TM-score 0.39, RMSD 0.84 Å
- 8WQA chain K against the predicted model Q8N998: TM-score 0.38, RMSD 2.39 Å
- 8WQA chain L against the predicted model Q8N998: TM-score 0.37, RMSD 1.41 Å
- 8WQD chain G against the predicted model Q8N998: TM-score 0.37, RMSD 0.31 Å
- 8WQB chain K against the predicted model Q8N998: TM-score 0.30, RMSD 1.05 Å
Elsewhere
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