UniProt Q8N5K1
CDGSH iron-sulfur domain-containing protein 2 (Q8N5K1)
CDGSH iron-sulfur domain-containing protein 2 (UniProt Q8N5K1): 8 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q8N5K1
- Protein
- CDGSH iron-sulfur domain-containing protein 2
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 3 · 2 records with a druggable one
Structures
9 records of Q8N5K1 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3FNV | Crystal Structure of Miner1: The Redox-active 2Fe-2S Protein Causative in Wolfram Syndrome 2 | x-ray diffraction | A, B | FES | — |
| 3FNV | Crystal structure of MINER1: the redox-active 2FE-2S protein causative in wolfram syndrome 2 | x-ray diffraction | A, B | — | — |
| 4OO7 | THE 1.55A CRYSTAL STRUCTURE of NAF1 (MINER1): THE REDOX-ACTIVE 2FE-2S PROTEIN | x-ray diffraction | A, B | FES | — |
| 4OO7 | The 1.55A crystal structure of NAF1 (MINER1): the redox-active 2FE-2S protein | x-ray diffraction | A, B | — | — |
| 4OOA | CRYSTAL STRUCTURE of NAF1 (MINER1): H114C THE REDOX-ACTIVE 2FE-2S PROTEIN | x-ray diffraction | A, B, C, D, E, F | FES | 2 (best 0.70) |
| 4OOA | Crystal structure of NAF1 (MINER1): H114C the redox-active 2FE-2S protein | x-ray diffraction | A, B, C, D, E, F | — | — |
| 7P0P | NAF-1 bound to M1 molecule | x-ray diffraction | A, B, C, D | FES, 49I | 1 (best 0.69) |
| 7P0P | Naf-1 bound to M1 molecule | x-ray diffraction | A, B, C, D | FES, 49I | — |
| Q8N5K1 | AlphaFold monomer V2.0 prediction for cdgsh iron-sulfur domain- containing protein 2 (Q8N5K1) | predicted | A | — | — |
Ligands
Experiment against prediction
- 4OOA chain C against the predicted model Q8N5K1: TM-score 0.98, RMSD 0.40 Å
- 4OOA chain C against the predicted model Q8N5K1: TM-score 0.98, RMSD 0.40 Å
- 4OO7 chain A against the predicted model Q8N5K1: TM-score 0.98, RMSD 0.41 Å
- 4OO7 chain A against the predicted model Q8N5K1: TM-score 0.98, RMSD 0.41 Å
- 4OOA chain D against the predicted model Q8N5K1: TM-score 0.98, RMSD 0.42 Å
- 4OOA chain D against the predicted model Q8N5K1: TM-score 0.98, RMSD 0.42 Å
- 3FNV chain A against the predicted model Q8N5K1: TM-score 0.97, RMSD 0.54 Å
- 3FNV chain A against the predicted model Q8N5K1: TM-score 0.97, RMSD 0.54 Å
- 3FNV chain B against the predicted model Q8N5K1: TM-score 0.97, RMSD 0.53 Å
- 3FNV chain B against the predicted model Q8N5K1: TM-score 0.97, RMSD 0.53 Å
Elsewhere
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