UniProt Q8N4T8
Carbonyl reductase family member 4 (Q8N4T8)
Carbonyl reductase family member 4 (UniProt Q8N4T8), EC 1.1.1.100: 4 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 68 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q8N4T8
- Protein
- Carbonyl reductase family member 4
- EC
- 1.1.1.100
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 68 · 4 records with a druggable one
Structures
5 records of Q8N4T8 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4CQL | Crystal structure of heterotetrameric human ketoacyl reductase complexed with NAD | x-ray diffraction | B, C, F, G, J, K, N, O | NAD | 17 (best 0.87) |
| 4CQL | Crystal structure of heterotetrameric human ketoacyl reductase complexed with NAD | x-ray diffraction | B, C, F, G, J, K, N, O | NAD | 17 (best 0.87) |
| 4CQM | Crystal structure of heterotetrameric human ketoacyl reductase complexed with NAD and NADP | x-ray diffraction | B, C, F, G, J, K, N, O | NAP | 17 (best 0.87) |
| 4CQM | Crystal structure of heterotetrameric human ketoacyl reductase complexed with NAD and NADP | x-ray diffraction | B, C, F, G, J, K, N, O | NAP | 17 (best 0.87) |
| Q8N4T8 | AlphaFold monomer V2.0 prediction for carbonyl reductase family member 4 (Q8N4T8) | predicted | A | — | — |
Ligands
Experiment against prediction
- 4CQM chain J against the predicted model Q8N4T8: TM-score 0.97, RMSD 0.73 Å
- 4CQM chain J against the predicted model Q8N4T8: TM-score 0.97, RMSD 0.73 Å
- 4CQM chain F against the predicted model Q8N4T8: TM-score 0.97, RMSD 0.73 Å
- 4CQM chain F against the predicted model Q8N4T8: TM-score 0.97, RMSD 0.73 Å
- 4CQM chain K against the predicted model Q8N4T8: TM-score 0.98, RMSD 0.92 Å
- 4CQM chain K against the predicted model Q8N4T8: TM-score 0.98, RMSD 0.92 Å
- 4CQM chain C against the predicted model Q8N4T8: TM-score 0.98, RMSD 0.87 Å
- 4CQM chain C against the predicted model Q8N4T8: TM-score 0.98, RMSD 0.87 Å
- 4CQM chain G against the predicted model Q8N4T8: TM-score 0.98, RMSD 0.90 Å
- 4CQM chain G against the predicted model Q8N4T8: TM-score 0.98, RMSD 0.90 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.