UniProt Q8N488
RING1 and YY1-binding protein (Q8N488)
RING1 and YY1-binding protein (UniProt Q8N488): 6 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 4 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8N488
- Protein
- RING1 and YY1-binding protein
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 4 · 3 records with a druggable one
Structures
7 records of Q8N488 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3IXS | Ring1B C-terminal domain/RYBP C-terminal domain Complex | x-ray diffraction | B, D, F, H, J, L | — | — |
| 3IXS | RING1B C-terminal DOMAIN/RYBP C-terminal domain complex | x-ray diffraction | B, D, F, H, J, L | — | — |
| 8PP6 | human RYBP-PRC1 bound to H2AK118ub1 nucleosome | electron microscopy | K | ZN | 1 (best 0.55) |
| 9DBY | ncPRC1RYBP bound to singly modified H2AK119Ub nucleosome | electron microscopy | M | ZN | 2 (best 0.69) |
| 9DDE | ncPRC1RYBP bound to H2AK119Ub/H1.4 chromatosome | electron microscopy | M | ZN | — |
| 9DG3 | ncPRC1RYBP Delta-linker mutant bound to singly modified H2AK119Ub nucleosome | electron microscopy | M | ZN | 1 (best 0.50) |
| Q8N488 | AlphaFold monomer V2.0 prediction for RING1 and YY1-binding protein (Q8N488) | predicted | A | — | — |
Ligands
- ZN · Zinc ion · in 4 records
Experiment against prediction
- 3IXS chain B against the predicted model Q8N488: TM-score 0.92, RMSD 0.40 Å
- 3IXS chain B against the predicted model Q8N488: TM-score 0.92, RMSD 0.40 Å
- 3IXS chain H against the predicted model Q8N488: TM-score 0.92, RMSD 0.79 Å
- 3IXS chain H against the predicted model Q8N488: TM-score 0.92, RMSD 0.79 Å
- 3IXS chain J against the predicted model Q8N488: TM-score 0.90, RMSD 0.46 Å
- 3IXS chain J against the predicted model Q8N488: TM-score 0.90, RMSD 0.46 Å
- 3IXS chain D against the predicted model Q8N488: TM-score 0.87, RMSD 0.89 Å
- 3IXS chain D against the predicted model Q8N488: TM-score 0.87, RMSD 0.89 Å
- 3IXS chain F against the predicted model Q8N488: TM-score 0.86, RMSD 0.83 Å
- 3IXS chain F against the predicted model Q8N488: TM-score 0.86, RMSD 0.83 Å
Elsewhere
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