UniProt Q8N3C0
Activating signal cointegrator 1 complex subunit 3 (Q8N3C0)
Activating signal cointegrator 1 complex subunit 3 (UniProt Q8N3C0), EC 3.6.4.12: 3 experimental structures and 1 predicted model on GenesisL1, 29 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- Q8N3C0
- Protein
- Activating signal cointegrator 1 complex subunit 3
- EC
- 3.6.4.12
- Experimental structures
- 3
- Predicted models
- 1
- Pockets
- 29 · 2 records with a druggable one
Structures
4 records of Q8N3C0 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6YXQ | Crystal structure of a DNA repair complex ASCC3-ASCC2 | x-ray diffraction | A | — | 9 (best 0.68) |
| 6YXQ | Crystal structure of a DNA repair complex ASCC3-ASCC2 | x-ray diffraction | A | — | — |
| 8ALZ | Cryo-EM structure of ASCC3 in complex with ASC1 | electron microscopy | B | — | 20 (best 0.85) |
| Q8N3C0 | AlphaFold monomer V2.0 prediction for activating signal cointegrator 1 complex subunit 3 (Q8N3C0) | predicted | A | — | — |
Experiment against prediction
- 8ALZ chain B against the predicted model Q8N3C0: TM-score 0.92, RMSD 3.92 Å
- 6YXQ chain A against the predicted model Q8N3C0: TM-score 0.58, RMSD 2.07 Å
- 6YXQ chain A against the predicted model Q8N3C0: TM-score 0.58, RMSD 2.07 Å
Elsewhere
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