UniProt Q8N2Z9
Centromere protein S (Q8N2Z9)
Centromere protein S (UniProt Q8N2Z9): 24 experimental structures and 1 predicted model on GenesisL1, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8N2Z9
- Protein
- Centromere protein S
- Experimental structures
- 24
- Predicted models
- 1
- Pockets
- 6 · 3 records with a druggable one
Structures
25 records of Q8N2Z9 in the MolNFT archive: 24 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4DRA | Crystal structure of MHF complex | x-ray diffraction | A, B, C, D | — | — |
| 4DRA | Crystal structure of mhf complex | x-ray diffraction | A, B, C, D | — | — |
| 4DRB | The crystal structure of FANCM bound MHF complex | x-ray diffraction | A, B, D, E, G, H | — | — |
| 4DRB | The crystal structure of fancm bound mhf complex | x-ray diffraction | A, B, D, E, G, H | — | — |
| 4E44 | Crystal structure of the hMHF1/hMHF2 Histone-Fold Tetramer | x-ray diffraction | A, C | — | — |
| 4E44 | Crystal structure of the HMHF1/HMHF2 histone-fold tetramer | x-ray diffraction | A, C | — | — |
| 4E45 | Crystal structure of the hMHF1/hMHF2 Histone-Fold Tetramer in Complex with Fanconi Anemia… | x-ray diffraction | A, C, F, H, K, M | — | — |
| 4E45 | Crystal structure of the HMHF1/HMHF2 histone-fold tetramer in complex with fanconi anemia… | x-ray diffraction | A, C, F, H, K, M | — | — |
| 4NDY | Human MHF1-MHF2 DNA complex | x-ray diffraction | C, G, A, I, J, K, Q, R, S, T | — | — |
| 4NDY | Human MHF1-MHF2 DNA complex | x-ray diffraction | C, G, A, I, J, K, Q, R, S, T | — | — |
| 4NE1 | Human MHF1 MHF2 DNA complexes | x-ray diffraction | C, G, A, I, J, K, Q, R, S, T, Y, a, c, e, f, g, k, l, m, n | — | — |
| 4NE1 | Human MHF1 MHF2 DNA complexes | x-ray diffraction | C, G, A, I, J, K, Q, R, S, T, Y, a, c, e, f, g, k, l, m, n | — | — |
| 4NE3 | Human MHF1-MHF2 complex | x-ray diffraction | A | — | — |
| 4NE3 | Human MHF1-MHF2 complex | x-ray diffraction | A | — | — |
| 4NE5 | Human MHF1-MHF2 complex | x-ray diffraction | A, C, E, G | — | — |
| 4NE5 | Human MHF1-MHF2 complex | x-ray diffraction | A, C, E, G | — | — |
| 4NE6 | Human MHF1-MHF2 complex | x-ray diffraction | A, C | — | — |
| 4NE6 | Human MHF1-MHF2 complex | x-ray diffraction | A, C | — | — |
| 7R5S | Structure of the human CCAN bound to alpha satellite DNA | electron microscopy | S | — | 1 (best 0.75) |
| 7R5S | Structure of the human ccan bound to alpha satellite DNA | electron microscopy | S | — | — |
| 7XHN | Structure of human inner kinetochore CCAN-DNA complex | electron microscopy | S | — | 2 (best 0.75) |
| 7XHO | Structure of human inner kinetochore CCAN complex | electron microscopy | S | — | 3 (best 0.73) |
| 7YWX | Structure of the human CCAN CENP-A alpha-satellite complex | electron microscopy | S | — | — |
| 7YWX | Structure of the human ccan cenp-a alpha-satellite complex | electron microscopy | S | — | — |
| Q8N2Z9 | AlphaFold monomer V2.0 prediction for centromere protein S (Q8N2Z9) | predicted | A | — | — |
Experiment against prediction
- 4DRA chain C against the predicted model Q8N2Z9: TM-score 0.97, RMSD 0.63 Å
- 4DRA chain C against the predicted model Q8N2Z9: TM-score 0.97, RMSD 0.63 Å
- 4NE5 chain C against the predicted model Q8N2Z9: TM-score 0.97, RMSD 0.65 Å
- 4NE5 chain C against the predicted model Q8N2Z9: TM-score 0.97, RMSD 0.65 Å
- 4E45 chain K against the predicted model Q8N2Z9: TM-score 0.97, RMSD 0.65 Å
- 4E45 chain K against the predicted model Q8N2Z9: TM-score 0.97, RMSD 0.65 Å
- 4NE5 chain A against the predicted model Q8N2Z9: TM-score 0.97, RMSD 0.65 Å
- 4NE5 chain A against the predicted model Q8N2Z9: TM-score 0.97, RMSD 0.65 Å
- 4NE5 chain G against the predicted model Q8N2Z9: TM-score 0.97, RMSD 0.65 Å
- 4NE5 chain G against the predicted model Q8N2Z9: TM-score 0.97, RMSD 0.65 Å
Elsewhere
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