UniProt Q8N201
Integrator complex subunit 1 (Q8N201)
Integrator complex subunit 1 (UniProt Q8N201): 6 experimental structures and 1 predicted model on GenesisL1, 13 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8N201
- Protein
- Integrator complex subunit 1
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 13 · 4 records with a druggable one
Structures
7 records of Q8N201 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7CUN | The structure of human Integrator-PP2A complex | electron microscopy | A | — | — |
| 7CUN | The structure of human integrator-PP2A complex | electron microscopy | A | — | — |
| 7PKS | Structural basis of Integrator-mediated transcription regulation | electron microscopy | a | — | 4 (best 0.88) |
| 7YCX | The structure of INTAC-PEC complex | electron microscopy | A | — | 4 (best 0.87) |
| 8RBX | Structure of Integrator-PP2A bound to a paused RNA polymerase II-DSIF-NELF-nucleosome complex | electron microscopy | a | — | 2 (best 0.88) |
| 8RBZ | Structure of Integrator-PP2A-SOSS-CTD post-termination complex | electron microscopy | a | — | 3 (best 0.89) |
| Q8N201 | AlphaFold monomer V2.0 prediction for integrator complex subunit 1 (Q8N201) | predicted | A | — | — |
Experiment against prediction
- 7CUN chain A against the predicted model Q8N201: TM-score 0.76, RMSD 3.06 Å
- 7CUN chain A against the predicted model Q8N201: TM-score 0.76, RMSD 3.06 Å
- 8RBZ chain a against the predicted model Q8N201: TM-score 0.54, RMSD 2.96 Å
- 7YCX chain A against the predicted model Q8N201: TM-score 0.46, RMSD 5.56 Å
- 7PKS chain a against the predicted model Q8N201: TM-score 0.43, RMSD 6.10 Å
- 8RBX chain a against the predicted model Q8N201: TM-score 0.42, RMSD 7.57 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.