UniProt Q8MNY2
Cathepsin B-like peptidase (C01 family) (Q8MNY2)
Cathepsin B-like peptidase (C01 family) (UniProt Q8MNY2): 20 experimental structures on GenesisL1, 7 ligands bound, 16 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q8MNY2
- Protein
- Cathepsin B-like peptidase (C01 family)
- Experimental structures
- 20
- Predicted models
- 0
- Ligands
- 7
- Pockets
- 16 · 5 records with a druggable one
Structures
20 records of Q8MNY2 in the MolNFT archive: 20 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3QSD | Structure of cathepsin B1 from Schistosoma mansoni in complex with CA074 inhibitor | x-ray diffraction | A | — | — |
| 3QSD | Structure of cathepsin B1 from schistosoma mansoni in complex with CA074 inhibitor | x-ray diffraction | A | — | — |
| 3S3Q | Structure of cathepsin B1 from Schistosoma mansoni in complex with K11017 inhibitor | x-ray diffraction | A | — | — |
| 3S3Q | Structure of cathepsin B1 from schistosoma mansoni in complex with K11017 inhibitor | x-ray diffraction | A | — | — |
| 3S3R | Structure of cathepsin B1 from Schistosoma mansoni in complex with K11777 inhibitor | x-ray diffraction | A, B, C | — | — |
| 3S3R | Structure of cathepsin B1 from schistosoma mansoni in complex with K11777 inhibitor | x-ray diffraction | A, B, C | — | — |
| 4I04 | Structure of zymogen of cathepsin B1 from Schistosoma mansoni | x-ray diffraction | A, B, C, D | — | — |
| 4I04 | Structure of zymogen of cathepsin B1 from schistosoma mansoni | x-ray diffraction | A, B, C, D | — | — |
| 4I05 | Structure of intermediate processing form of cathepsin B1 from Schistosoma mansoni | x-ray diffraction | A | — | — |
| 4I05 | Structure of intermediate processing form of cathepsin B1 from schistosoma mansoni | x-ray diffraction | A | — | — |
| 4I07 | Structure of mature form of cathepsin B1 from Schistosoma mansoni | x-ray diffraction | A | — | — |
| 4I07 | Structure of mature form of cathepsin B1 from schistosoma mansoni | x-ray diffraction | A | — | — |
| 5OGQ | Structure of cathepsin B1 from schistosoma mansoni in complex with WRR391 inhibitor | x-ray diffraction | A, B, C | 9U8 | — |
| 5OGR | Structure of cathepsin B1 from Schistosoma mansoni in complex with WRR286 inhibitor | x-ray diffraction | A, B, C | VS4 | 7 (best 0.76) |
| 5OGR | Structure of cathepsin B1 from schistosoma mansoni in complex with WRR286 inhibitor | x-ray diffraction | A, B, C | VS4 | — |
| 6YI7 | Structure of cathepsin B1 from Schistosoma mansoni (SmCB1) in complex with an azanitrile inhibitor | x-ray diffraction | A | ORW | 2 (best 0.51) |
| 6YI7 | Structure of cathepsin B1 from schistosoma mansoni (SMCB1) in complex with an azanitrile inhibitor | x-ray diffraction | A | — | — |
| 8CC2 | Cathepsin B1 from Schistosoma mansoni in complex with gallinamide A | x-ray diffraction | AAA | GN9, NA | 2 (best 0.53) |
| 8CCU | Cathepsin B1 from Schistosoma mansoni in complex with gallinamide analog 1 | x-ray diffraction | AAA | U9X, NA | 2 (best 0.51) |
| 8CD9 | Cathepsin B1 from Schistosoma mansoni in complex with gallinamide analog 6 | x-ray diffraction | AAA | UA9, NA | 3 (best 0.51) |
Ligands
- NA · Sodium ion · in 3 records
- VS4 · 3-[[N-[4-methyl-piperazinyl]carbonyl]-phenylalaninyl-amino]-5-phenyl-pentane-1-sulfonic acid benzyloxy-amide · in 2 records
- 9U8 · Ethyl 1-[[(2~{S})-3-(4-hydroxyphenyl)-1-oxidanylidene-1-[[(3~{S})-1-phenyl-5-pyridin-2-ylsulfonyl-pentan-3-yl]amino]propan-2-yl]carbamoyl]piperidine-4-carboxylate · in 1 record
- GN9 · gallinamide A, bound form · in 1 record
- ORW · 1-[(2~{S})-1-[[iminomethyl(methyl)amino]-methyl-amino]-4-methyl-1-oxidanylidene-pentan-2-yl]-3-(phenylmethyl)urea · in 1 record
- U9X · [(2~{S})-1-[[(2~{S})-1-[[(2~{S})-5-[(2~{S})-3-methoxy-2-(2-methylpropyl)-5-oxidanylidene-2~{H}-pyrrol-1-yl]-5-oxidanylidene-pentan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl] (2~{S},3~{S})-2-(dimethylamino)-3-methyl-pentanoate · in 1 record
- UA9 · [(2~{S})-1-[[(2~{S})-1-[[(2~{S})-5-[(2~{S})-3-methoxy-5-oxidanylidene-2-(phenylmethyl)-2~{H}-pyrrol-1-yl]-5-oxidanylidene-pentan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl] (2~{S})-2-(dimethylamino)-3-phenyl-propanoate · in 1 record
Elsewhere
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