UniProt Q8ML92
Protein aveugle (Q8ML92)
Protein aveugle (UniProt Q8ML92): 6 experimental structures and 1 predicted model on GenesisL1, 12 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8ML92
- Protein
- Protein aveugle
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 12 · 2 records with a druggable one
Structures
7 records of Q8ML92 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3BS5 | Crystal Structure of hCNK2-SAM/dHYP-SAM Complex | x-ray diffraction | A | — | — |
| 3BS5 | Crystal structure of HCNK2-SAM/DHYP-SAM complex | x-ray diffraction | A | — | — |
| 3BS7 | Crystal structure of the Sterile Alpha Motif (SAM) domain of Hyphen/Aveugle | x-ray diffraction | A, B | — | — |
| 3BS7 | Crystal structure of the sterile alpha motif (SAM) domain of HYPHEN/AVEUGLE | x-ray diffraction | A, B | — | — |
| 8BW8 | Crystal structure of the dCNK-SAM-CRIC-PDZ/dHYP-SAM complex | x-ray diffraction | A, C, E | — | 9 (best 0.77) |
| 8BW9 | Cryo-EM structure of the RAF activating complex KSR-MEK-CNK-HYP | electron microscopy | A | — | 3 (best 0.84) |
| Q8ML92 | AlphaFold monomer V2.0 prediction for protein aveugle (Q8ML92) | predicted | A | — | — |
Experiment against prediction
- 3BS7 chain A against the predicted model Q8ML92: TM-score 0.99, RMSD 0.30 Å
- 3BS7 chain A against the predicted model Q8ML92: TM-score 0.99, RMSD 0.30 Å
- 3BS7 chain B against the predicted model Q8ML92: TM-score 0.99, RMSD 0.34 Å
- 3BS7 chain B against the predicted model Q8ML92: TM-score 0.99, RMSD 0.34 Å
- 8BW8 chain A against the predicted model Q8ML92: TM-score 0.98, RMSD 0.50 Å
- 8BW8 chain E against the predicted model Q8ML92: TM-score 0.97, RMSD 0.68 Å
- 8BW8 chain C against the predicted model Q8ML92: TM-score 0.97, RMSD 0.70 Å
- 3BS5 chain A against the predicted model Q8ML92: TM-score 0.96, RMSD 0.94 Å
- 3BS5 chain A against the predicted model Q8ML92: TM-score 0.96, RMSD 0.94 Å
- 8BW9 chain A against the predicted model Q8ML92: TM-score 0.94, RMSD 0.87 Å
Elsewhere
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