UniProt Q8LFJ6
DNA-directed RNA polymerases II, IV and V subunit 10 (Q8LFJ6)
DNA-directed RNA polymerases II, IV and V subunit 10 (UniProt Q8LFJ6): 8 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 7 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q8LFJ6
- Protein
- DNA-directed RNA polymerases II, IV and V subunit 10
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 7 · 6 records with a druggable one
Structures
9 records of Q8LFJ6 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7EU0 | The cryo-EM structure of A. thaliana Pol IV-RDR2 backtracked complex | electron microscopy | J | ZN | 1 (best 0.77) |
| 7EU0 | The cryo-EM structure of a. thaliana pol IV-RDR2 backtracked complex | electron microscopy | J | ZN | — |
| 7EU1 | The cryo-EM structure of a. thaliana pol IV-RDR2 holoenzyme | electron microscopy | J | ZN | — |
| 8HYJ | A cryo-EM structure of KTF1-bound polymerase V transcription elongation complex | electron microscopy | J | ZN | 1 (best 0.73) |
| 8XMB | NTP-bound Pol IV transcription elongation complex | electron microscopy | J | ZN | 2 (best 0.73) |
| 8XMC | Post-translocated Pol IV transcription elongation complex | electron microscopy | J | ZN | 1 (best 0.88) |
| 8XMD | Pre-translocated Pol IV transcription elongation complex | electron microscopy | J | ZN | 1 (best 0.87) |
| 8XME | Backtracked Pol IV transcription elongation complex | electron microscopy | J | ZN | 1 (best 0.73) |
| Q8LFJ6 | AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerases II, IV and V subunit 10 (Q8LFJ6) | predicted | A | — | — |
Ligands
- ZN · Zinc ion · in 8 records
Experiment against prediction
- 8HYJ chain J against the predicted model Q8LFJ6: TM-score 0.96, RMSD 0.61 Å
- 7EU0 chain J against the predicted model Q8LFJ6: TM-score 0.95, RMSD 0.69 Å
- 7EU0 chain J against the predicted model Q8LFJ6: TM-score 0.95, RMSD 0.69 Å
- 8XMC chain J against the predicted model Q8LFJ6: TM-score 0.95, RMSD 0.72 Å
- 8XMB chain J against the predicted model Q8LFJ6: TM-score 0.94, RMSD 0.76 Å
- 8XMD chain J against the predicted model Q8LFJ6: TM-score 0.94, RMSD 0.77 Å
- 8XME chain J against the predicted model Q8LFJ6: TM-score 0.94, RMSD 0.76 Å
- 7EU1 chain J against the predicted model Q8LFJ6: TM-score 0.94, RMSD 0.70 Å
Elsewhere
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