UniProt Q8K203
Endonuclease 8-like 3 (Q8K203)
Endonuclease 8-like 3 (UniProt Q8K203), EC 3.2.2.-, 4.2.99.18: 6 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 16 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q8K203
- Protein
- Endonuclease 8-like 3
- EC
- 3.2.2.-, 4.2.99.18
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 16 · 3 records with a druggable one
Structures
7 records of Q8K203 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3W0F | Crystal structure of mouse Endonuclease VIII-LIKE 3 (mNEIL3) | x-ray diffraction | A | — | — |
| 3W0F | Crystal structure of mouse endonuclease VIII-like 3 (MNEIL3) | x-ray diffraction | A | — | — |
| 7OMK | The NMR structure of the Zf-GRF domains from the mouse Endonuclease VIII-LIKE 3 (mNEIL3) | solution nmr | A | — | — |
| 7OMK | The NMR structure of the zf-grf domains from the mouse endonuclease VIII-like 3 (MNEIL3) | solution nmr | A | — | — |
| 7Z5A | Crystal structure of the trapped complex of mouse Endonuclease VIII-LIKE 3 (mNEIL3) and hairpin DNA… | x-ray diffraction | A | ZN | 5 (best 0.57) |
| 8B9N | Crystal structure of NEI domain of mouse NEIL3 trapped in covalent complex with ssDNA with abasic… | x-ray diffraction | A, C | ZN | 5 (best 0.56) |
| Q8K203 | AlphaFold monomer V2.0 prediction for endonuclease 8-like 3 (Q8K203) | predicted | A | — | 6 (best 0.65) |
Ligands
- ZN · Zinc ion · in 2 records
Experiment against prediction
- 3W0F chain A against the predicted model Q8K203: TM-score 0.99, RMSD 0.71 Å
- 3W0F chain A against the predicted model Q8K203: TM-score 0.99, RMSD 0.71 Å
- 8B9N chain C against the predicted model Q8K203: TM-score 0.99, RMSD 0.68 Å
- 8B9N chain A against the predicted model Q8K203: TM-score 0.99, RMSD 0.73 Å
- 7Z5A chain A against the predicted model Q8K203: TM-score 0.94, RMSD 1.55 Å
- 7OMK chain A against the predicted model Q8K203: TM-score 0.66, RMSD 3.01 Å
- 7OMK chain A against the predicted model Q8K203: TM-score 0.66, RMSD 3.01 Å
Elsewhere
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