UniProt Q8JSZ3
GP38 (Q8JSZ3)
GP38 (UniProt Q8JSZ3): 12 experimental structures on GenesisL1, 7 ligands bound, 70 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q8JSZ3
- Protein
- GP38
- Experimental structures
- 12
- Predicted models
- 0
- Ligands
- 7
- Pockets
- 70 · 6 records with a druggable one
Structures
12 records of Q8JSZ3 in the MolNFT archive: 12 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7A59 | Crimean-Congo Hemorrhagic Fever Virus Envelope Glycoprotein Gc W1191H/W1197A/W1199A Mutant in… | x-ray diffraction | A, B, C | NAG, FUC, CL, PO4 | 20 (best 0.85) |
| 7A59 | Crimean-congo hemorrhagic fever virus envelope glycoprotein gc W1191H/W1197A/W1199A mutant in… | x-ray diffraction | A, B, C | NAG, FUC, CL, PO4 | — |
| 7FGF | Cryo-EM structure of cchfv envelope protein gc in postfusion conformation | electron microscopy | A, B, C | — | — |
| 7L7R | CCHFV Gc prefusion monomer bound to ADI-36121 and ADI-37801 Fabs | x-ray diffraction | G | NAG, BMA | 7 (best 0.75) |
| 7L7R | Cchfv gc prefusion monomer bound to adi-36121 and adi-37801 fabs | x-ray diffraction | G | NAG | — |
| 8JKD | Cryo-EM structure of CCHFV envelope protein Gc trimer in complex with Gc13 Fab | electron microscopy | A, B, C | — | 20 (best 0.86) |
| 8JLW | CCHFV envelope protein Gc in complex with Gc8 | electron microscopy | A | — | 1 (best 0.39) |
| 8JLX | CCHFV envelope protein Gc in complex with Gc13 | electron microscopy | A | — | 1 (best 0.44) |
| 8VVL | CCHFV GP38 bound to c13G8 Fab | x-ray diffraction | A | NAG, SO4, CL | 3 (best 0.44) |
| 8VWW | CCHFV GP38 bound to ADI-46152 and ADI-58048 Fabs | electron microscopy | A | — | 5 (best 0.60) |
| 9AVF | CCHFV GP38-GnH-DS heterodimer | x-ray diffraction | A, B, C, D | NAG, A2G | 6 (best 0.61) |
| 9B8J | GP38-GnH-DS-Gc in the pre-fusion conformation | electron microscopy | A, B, D | NAG, BMA | 7 (best 0.65) |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 7 records
- CL · Chloride ion · in 3 records
- BMA · beta-D-mannopyranose · in 2 records
- FUC · alpha-L-fucopyranose · in 2 records
- PO4 · Phosphate ion · in 2 records
- A2G · 2-acetamido-2-deoxy-alpha-D-galactopyranose · in 1 record
- SO4 · Sulfate ion · in 1 record
Elsewhere
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