UniProt Q8IZI9
Interferon lambda-3 (Q8IZI9)
Interferon lambda-3 (UniProt Q8IZI9): 4 experimental structures and 1 predicted model on GenesisL1, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8IZI9
- Protein
- Interferon lambda-3
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 2 · 1 record with a druggable one
Structures
5 records of Q8IZI9 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3HHC | Interferon-lambda is functionally an interferon but structurally related to the IL-10 family | x-ray diffraction | A, B, C, D | — | — |
| 3HHC | Interferon-lambda is functionally an interferon but structurally related to the il-10 family | x-ray diffraction | A, B, C, D | — | — |
| 5T5W | Structure of an affinity matured lambda-IFN/IFN-lambdaR1/IL-10Rbeta receptor complex | x-ray diffraction | C | — | 2 (best 0.71) |
| 5T5W | Structure of an affinity matured lambda-IFN/IFN-LAMBDAR1/IL-10RBETA receptor complex | x-ray diffraction | C | — | — |
| Q8IZI9 | AlphaFold monomer V2.0 prediction for interferon lambda-3 (Q8IZI9) | predicted | A | — | — |
Experiment against prediction
- 5T5W chain C against the predicted model Q8IZI9: TM-score 0.97, RMSD 0.83 Å
- 5T5W chain C against the predicted model Q8IZI9: TM-score 0.97, RMSD 0.83 Å
- 3HHC chain A against the predicted model Q8IZI9: TM-score 0.97, RMSD 1.18 Å
- 3HHC chain A against the predicted model Q8IZI9: TM-score 0.97, RMSD 1.18 Å
- 3HHC chain C against the predicted model Q8IZI9: TM-score 0.96, RMSD 1.02 Å
- 3HHC chain C against the predicted model Q8IZI9: TM-score 0.96, RMSD 1.02 Å
- 3HHC chain B against the predicted model Q8IZI9: TM-score 0.95, RMSD 1.60 Å
- 3HHC chain B against the predicted model Q8IZI9: TM-score 0.95, RMSD 1.60 Å
- 3HHC chain D against the predicted model Q8IZI9: TM-score 0.94, RMSD 1.02 Å
- 3HHC chain D against the predicted model Q8IZI9: TM-score 0.94, RMSD 1.02 Å
Elsewhere
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