UniProt Q8IYV9
Izumo sperm-egg fusion protein 1 (Q8IYV9)
Izumo sperm-egg fusion protein 1 (UniProt Q8IYV9): 14 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 19 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8IYV9
- Protein
- Izumo sperm-egg fusion protein 1
- Experimental structures
- 14
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 19 · 2 records with a druggable one
Structures
15 records of Q8IYV9 in the MolNFT archive: 14 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5F4E | Crystal structure of the human sperm Izumo1 and egg Juno complex | x-ray diffraction | A | NAG | — |
| 5F4E | Crystal structure of the human sperm IZUMO1 and egg juno complex | x-ray diffraction | A | — | — |
| 5F4T | Crystal structure of the human sperm Izumo1 residues 22-254 | x-ray diffraction | A | NAG | — |
| 5F4T | Crystal structure of the human sperm IZUMO1 residues 22-254 | x-ray diffraction | A | — | — |
| 5F4V | Crystal structure of the human sperm Izumo1 residues 22-268 | x-ray diffraction | A | NAG | — |
| 5F4V | Crystal structure of the human sperm IZUMO1 residues 22-268 | x-ray diffraction | A | — | — |
| 5JK9 | Crystal structure of human IZUMO1 | x-ray diffraction | A, B, C, D, E, F | NAG | — |
| 5JK9 | Crystal structure of human IZUMO1 | x-ray diffraction | A, B, C, D, E, F | — | — |
| 5JKC | Crystal structure of human IZUMO1-JUNO complex (crystal form 1) | x-ray diffraction | A | NAG | 3 (best 0.50) |
| 5JKC | Crystal structure of human IZUMO1-juno complex (crystal form 1) | x-ray diffraction | A | — | — |
| 5JKD | Crystal structure of human IZUMO1-JUNO complex (crystal form 2) | x-ray diffraction | A | NAG | 3 (best 0.63) |
| 5JKD | Crystal structure of human IZUMO1-juno complex (crystal form 2) | x-ray diffraction | A | — | — |
| 5JKE | Crystal structure of human IZUMO1-JUNO complex (crystal form 3) | x-ray diffraction | A, C | NAG, SO4 | 13 (best 0.65) |
| 5JKE | Crystal structure of human IZUMO1-juno complex (crystal form 3) | x-ray diffraction | A, C | — | — |
| Q8IYV9 | AlphaFold monomer V2.0 prediction for izumo sperm-egg fusion protein 1 (Q8IYV9) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5JKD chain A against the predicted model Q8IYV9: TM-score 0.98, RMSD 0.99 Å
- 5JKD chain A against the predicted model Q8IYV9: TM-score 0.98, RMSD 0.99 Å
- 5JK9 chain E against the predicted model Q8IYV9: TM-score 0.98, RMSD 0.94 Å
- 5JK9 chain E against the predicted model Q8IYV9: TM-score 0.98, RMSD 0.94 Å
- 5JKE chain A against the predicted model Q8IYV9: TM-score 0.97, RMSD 1.05 Å
- 5JKE chain A against the predicted model Q8IYV9: TM-score 0.97, RMSD 1.05 Å
- 5JKC chain A against the predicted model Q8IYV9: TM-score 0.97, RMSD 1.12 Å
- 5JKC chain A against the predicted model Q8IYV9: TM-score 0.97, RMSD 1.12 Å
- 5JKE chain C against the predicted model Q8IYV9: TM-score 0.97, RMSD 1.15 Å
- 5JK9 chain B against the predicted model Q8IYV9: TM-score 0.97, RMSD 1.10 Å
Elsewhere
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