UniProt Q8IY81
pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3 (Q8IY81)
pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3 (UniProt Q8IY81), EC 2.1.1.-: 11 experimental structures and 1 predicted model on GenesisL1, 13 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q8IY81
- Protein
- pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3
- EC
- 2.1.1.-
- Experimental structures
- 11
- Predicted models
- 1
- Pockets
- 13 · 8 records with a druggable one
Structures
12 records of Q8IY81 in the MolNFT archive: 11 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8FKP | Human nucleolar pre-60S ribosomal subunit (State A1) | electron microscopy | SJ | — | — |
| 8FKQ | Human nucleolar pre-60S ribosomal subunit (State A2) | electron microscopy | SJ | — | 1 (best 0.89) |
| 8FKR | Human nucleolar pre-60S ribosomal subunit (State B1) | electron microscopy | SJ | — | 1 (best 0.87) |
| 8FKS | Human nucleolar pre-60S ribosomal subunit (State B2) | electron microscopy | SJ | — | 1 (best 0.87) |
| 8FKT | Human nucleolar pre-60S ribosomal subunit (State C1) | electron microscopy | SJ | — | 1 (best 0.89) |
| 8FKU | Human nucleolar pre-60S ribosomal subunit (State C2) | electron microscopy | SJ | — | 1 (best 0.84) |
| 8FKV | Human nucleolar pre-60S ribosomal subunit (State D1) | electron microscopy | SJ | — | — |
| 8FKW | Human nucleolar pre-60S ribosomal subunit (State D2) | electron microscopy | SJ | — | 1 (best 0.88) |
| 8FKX | Human nucleolar pre-60S ribosomal subunit (State E) | electron microscopy | SJ | — | 1 (best 0.87) |
| 8FKY | Human nucleolar pre-60S ribosomal subunit (State F) | electron microscopy | SJ | — | 1 (best 0.88) |
| 8IR1 | human nuclear pre-60S ribosomal particle - State A | electron microscopy | 9 | — | — |
| Q8IY81 | AlphaFold monomer V2.0 prediction for pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3 (Q8IY81) | predicted | A | — | 5 (best 0.48) |
Experiment against prediction
- 8IR1 chain 9 against the predicted model Q8IY81: TM-score 0.78, RMSD 1.78 Å
- 8FKQ chain SJ against the predicted model Q8IY81: TM-score 0.72, RMSD 2.52 Å
- 8FKR chain SJ against the predicted model Q8IY81: TM-score 0.72, RMSD 2.40 Å
- 8FKP chain SJ against the predicted model Q8IY81: TM-score 0.72, RMSD 2.45 Å
- 8FKS chain SJ against the predicted model Q8IY81: TM-score 0.71, RMSD 2.50 Å
- 8FKW chain SJ against the predicted model Q8IY81: TM-score 0.64, RMSD 2.62 Å
- 8FKV chain SJ against the predicted model Q8IY81: TM-score 0.59, RMSD 2.59 Å
- 8FKU chain SJ against the predicted model Q8IY81: TM-score 0.54, RMSD 2.80 Å
- 8FKT chain SJ against the predicted model Q8IY81: TM-score 0.53, RMSD 2.88 Å
- 8FKX chain SJ against the predicted model Q8IY81: TM-score 0.30, RMSD 4.39 Å
Elsewhere
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