UniProt Q8IWZ8
SURP and G-patch domain-containing protein 1 (Q8IWZ8)
SURP and G-patch domain-containing protein 1 (UniProt Q8IWZ8): 3 experimental structures and 1 predicted model on GenesisL1, 10 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8IWZ8
- Protein
- SURP and G-patch domain-containing protein 1
- Experimental structures
- 3
- Predicted models
- 1
- Pockets
- 10 · 4 records with a druggable one
Structures
4 records of Q8IWZ8 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8EJM | Crystal structure of human DEAH-box helicase DHX15 in complex with SUGP1 G-patch | x-ray diffraction | B | — | 2 (best 0.84) |
| 8GXL | Human SUGP1 433-577 | x-ray diffraction | A, B | — | 2 (best 0.76) |
| 8GXM | Human SUGP1 433-586 | x-ray diffraction | A, B | — | 3 (best 0.74) |
| Q8IWZ8 | AlphaFold monomer V2.0 prediction for surp and G-patch domain- containing protein 1 (Q8IWZ8) | predicted | A | — | 3 (best 0.66) |
Experiment against prediction
- 8GXM chain A against the predicted model Q8IWZ8: TM-score 0.59, RMSD 3.08 Å
- 8GXL chain A against the predicted model Q8IWZ8: TM-score 0.57, RMSD 3.17 Å
- 8GXL chain B against the predicted model Q8IWZ8: TM-score 0.57, RMSD 3.21 Å
- 8EJM chain B against the predicted model Q8IWZ8: TM-score 0.56, RMSD 2.84 Å
- 8GXM chain B against the predicted model Q8IWZ8: TM-score 0.46, RMSD 3.77 Å
Elsewhere
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