UniProt Q8IWT3
Cullin-9 (Q8IWT3)
Cullin-9 (UniProt Q8IWT3): 5 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 59 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8IWT3
- Protein
- Cullin-9
- Experimental structures
- 5
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 59 · 3 records with a druggable one
Structures
6 records of Q8IWT3 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2JUF | NMR solution structure of PARC CPH Domain. NESG Target HR3443B/SGC-Toronto | solution nmr | A | — | — |
| 2JUF | NMR solution structure of parc cph domain. nesg target HR3443B/SGC- toronto | solution nmr | A | — | — |
| 8Q7E | Structure of CUL9-RBX1 ubiquitin E3 ligase complex - hexameric assembly | electron microscopy | A, B, E, F, I, J | — | 20 (best 0.79) |
| 8Q7H | Structure of CUL9-RBX1 ubiquitin E3 ligase complex in unneddylated and neddylated conformation… | electron microscopy | A, B | ZN | 19 (best 0.82) |
| 8RHZ | Structure of CUL9-RBX1 ubiquitin E3 ligase complex in unneddylated conformation - symmetry expanded… | electron microscopy | A, B | — | 20 (best 0.85) |
| Q8IWT3 | AlphaFold monomer V2.0 prediction for cullin-9 (Q8IWT3) | predicted | A | — | — |
Ligands
- ZN · Zinc ion · in 1 record
Experiment against prediction
- 2JUF chain A against the predicted model Q8IWT3: TM-score 0.90, RMSD 1.03 Å
- 2JUF chain A against the predicted model Q8IWT3: TM-score 0.90, RMSD 1.03 Å
- 8Q7E chain I against the predicted model Q8IWT3: TM-score 0.77, RMSD 5.01 Å
- 8Q7E chain A against the predicted model Q8IWT3: TM-score 0.76, RMSD 5.21 Å
- 8Q7E chain E against the predicted model Q8IWT3: TM-score 0.76, RMSD 5.26 Å
- 8Q7E chain J against the predicted model Q8IWT3: TM-score 0.75, RMSD 4.98 Å
- 8Q7E chain F against the predicted model Q8IWT3: TM-score 0.75, RMSD 5.48 Å
- 8Q7E chain B against the predicted model Q8IWT3: TM-score 0.75, RMSD 5.50 Å
- 8Q7H chain B against the predicted model Q8IWT3: TM-score 0.70, RMSD 5.69 Å
- 8RHZ chain B against the predicted model Q8IWT3: TM-score 0.69, RMSD 5.76 Å
Elsewhere
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