UniProt Q8IVU3
Probable E3 ubiquitin-protein ligase HERC6 (Q8IVU3)
Probable E3 ubiquitin-protein ligase HERC6 (UniProt Q8IVU3), EC 2.3.2.26: 2 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 3 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q8IVU3
- Protein
- Probable E3 ubiquitin-protein ligase HERC6
- EC
- 2.3.2.26
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 3 · 0 records with a druggable one
Structures
3 records of Q8IVU3 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5W87 | Crystal structure of the C-terminal lobe of the human HERC6 HECT domain | x-ray diffraction | A, B | PO4 | 3 (best 0.42) |
| 5W87 | Crystal structure of the C-terminal lobe of the human HERC6 hect domain | x-ray diffraction | A, B | PO4 | — |
| Q8IVU3 | AlphaFold monomer V2.0 prediction for probable E3 ubiquitin-protein ligase HERC6 (Q8IVU3) | predicted | A | — | — |
Ligands
- PO4 · Phosphate ion · in 2 records
Experiment against prediction
- 5W87 chain B against the predicted model Q8IVU3: TM-score 0.68, RMSD 1.86 Å
- 5W87 chain B against the predicted model Q8IVU3: TM-score 0.68, RMSD 1.86 Å
- 5W87 chain A against the predicted model Q8IVU3: TM-score 0.67, RMSD 2.29 Å
- 5W87 chain A against the predicted model Q8IVU3: TM-score 0.67, RMSD 2.29 Å
Elsewhere
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