UniProt Q8IUX4
DNA dC->dU-editing enzyme APOBEC-3F (Q8IUX4)
DNA dC->dU-editing enzyme APOBEC-3F (UniProt Q8IUX4), EC 3.5.4.-, 3.5.4.38: 18 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 39 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q8IUX4
- Protein
- DNA dC->dU-editing enzyme APOBEC-3F
- EC
- 3.5.4.-, 3.5.4.38
- Experimental structures
- 18
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 39 · 5 records with a druggable one
Structures
19 records of Q8IUX4 in the MolNFT archive: 18 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3WUS | Crystal Structure of the Vif-Binding Domain of Human APOBEC3F | x-ray diffraction | A, B | — | — |
| 3WUS | Crystal structure of the vif-binding domain of human APOBEC3F | x-ray diffraction | A, B | — | — |
| 4IOU | Crystal structure of the HIV-1 Vif binding, catalytically active domain of APOBEC3F | x-ray diffraction | A, B, C, D | — | — |
| 4IOU | Crystal structure of the HIV-1 vif binding, catalytically active domain of APOBEC3F | x-ray diffraction | A, B, C, D | — | — |
| 4J4J | Crystal structure of the APOBEC3F Vif binding domain | x-ray diffraction | A, B | — | — |
| 4J4J | Crystal structure of the APOBEC3F vif binding domain | x-ray diffraction | A, B | — | — |
| 5HX4 | Zinc-Free APOBEC3F Catalytic Domain Crystal Structure | x-ray diffraction | A, B | — | — |
| 5HX4 | Zinc-free APOBEC3F catalytic domain crystal structure | x-ray diffraction | A, B | — | — |
| 5HX5 | APOBEC3F Catalytic Domain Crystal Structure | x-ray diffraction | A, B | ZN | 4 (best 0.67) |
| 5HX5 | APOBEC3F catalytic domain crystal structure | x-ray diffraction | A, B | — | — |
| 5W2M | APOBEC3F Catalytic Domain Complex with a Single-Stranded DNA | x-ray diffraction | A, B, C, D, J, K, L, M | ZN | 18 (best 0.81) |
| 5W2M | APOBEC3F catalytic domain complex with a single-stranded DNA | x-ray diffraction | A, B, C, D, J, K, L, M | ZN | — |
| 5ZVA | APOBEC3F Chimeric Catalytic Domain in Complex with DNA(dC9) | x-ray diffraction | A, B | ZN | 3 (best 0.62) |
| 5ZVA | APOBEC3F chimeric catalytic domain in complex with DNA(DC9) | x-ray diffraction | A, B | ZN | — |
| 5ZVB | APOBEC3F Chimeric Catalytic Domain in Complex with DNA(dT9) | x-ray diffraction | A, B | ZN | 2 (best 0.62) |
| 5ZVB | APOBEC3F chimeric catalytic domain in complex with DNA(DT9) | x-ray diffraction | A, B | ZN | — |
| 6NIL | cryoEM structure of the truncated HIV-1 Vif/CBFbeta/A3F complex | electron microscopy | A, D, G, J | ZN | 12 (best 0.76) |
| 6NIL | Cryoem structure of the truncated HIV-1 VIF/CBFBETA/A3F complex | electron microscopy | A, D, G, J | ZN | — |
| Q8IUX4 | AlphaFold monomer V2.0 prediction for DNA dc->du-editing enzyme apobec-3F (Q8IUX4) | predicted | A | — | — |
Ligands
- ZN · Zinc ion · in 9 records
Experiment against prediction
- 5HX5 chain B against the predicted model Q8IUX4: TM-score 0.99, RMSD 0.54 Å
- 5HX5 chain B against the predicted model Q8IUX4: TM-score 0.99, RMSD 0.54 Å
- 5HX4 chain B against the predicted model Q8IUX4: TM-score 0.98, RMSD 0.76 Å
- 5HX4 chain B against the predicted model Q8IUX4: TM-score 0.98, RMSD 0.76 Å
- 5HX4 chain A against the predicted model Q8IUX4: TM-score 0.98, RMSD 0.92 Å
- 5HX4 chain A against the predicted model Q8IUX4: TM-score 0.98, RMSD 0.92 Å
- 3WUS chain B against the predicted model Q8IUX4: TM-score 0.98, RMSD 0.96 Å
- 3WUS chain B against the predicted model Q8IUX4: TM-score 0.98, RMSD 0.96 Å
- 3WUS chain A against the predicted model Q8IUX4: TM-score 0.98, RMSD 0.96 Å
- 3WUS chain A against the predicted model Q8IUX4: TM-score 0.98, RMSD 0.96 Å
Elsewhere
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