UniProt Q8IUH5
Palmitoyltransferase ZDHHC17 (Q8IUH5)
Palmitoyltransferase ZDHHC17 (UniProt Q8IUH5), EC 2.3.1.225: 6 experimental structures and 1 predicted model on GenesisL1, 20 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8IUH5
- Protein
- Palmitoyltransferase ZDHHC17
- EC
- 2.3.1.225
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 20 · 3 records with a druggable one
Structures
7 records of Q8IUH5 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3EU9 | The ankyrin repeat domain of Huntingtin interacting protein 14 | x-ray diffraction | A, B, C | — | — |
| 3EU9 | The ankyrin repeat domain of huntingtin interacting protein 14 | x-ray diffraction | A, B, C | — | — |
| 5W7I | X-ray structure of ankyrin repeat domain of DHHC17 in complex with Snap25b peptide | x-ray diffraction | A, C | — | 6 (best 0.70) |
| 5W7I | X-ray structure of ankyrin repeat domain of DHHC17 in complex with SNAP25B peptide | x-ray diffraction | A, C | — | — |
| 5W7J | X-ray structure of the E89A variant of ankyrin repeat domain of DHHC17 in complex with Snap25b… | x-ray diffraction | A, C | — | 6 (best 0.69) |
| 5W7J | X-ray structure of the E89A variant of ankyrin repeat domain of DHHC17 in complex with SNAP25B… | x-ray diffraction | A, C | — | — |
| Q8IUH5 | AlphaFold monomer V2.0 prediction for palmitoyltransferase ZDHHC17 (Q8IUH5) | predicted | A | — | 8 (best 0.69) |
Experiment against prediction
- 3EU9 chain C against the predicted model Q8IUH5: TM-score 0.99, RMSD 0.51 Å
- 3EU9 chain C against the predicted model Q8IUH5: TM-score 0.99, RMSD 0.51 Å
- 5W7J chain A against the predicted model Q8IUH5: TM-score 0.98, RMSD 0.73 Å
- 5W7J chain A against the predicted model Q8IUH5: TM-score 0.98, RMSD 0.73 Å
- 5W7I chain A against the predicted model Q8IUH5: TM-score 0.98, RMSD 0.74 Å
- 5W7I chain A against the predicted model Q8IUH5: TM-score 0.98, RMSD 0.74 Å
- 3EU9 chain B against the predicted model Q8IUH5: TM-score 0.98, RMSD 0.91 Å
- 3EU9 chain B against the predicted model Q8IUH5: TM-score 0.98, RMSD 0.91 Å
- 5W7I chain C against the predicted model Q8IUH5: TM-score 0.98, RMSD 0.97 Å
- 5W7I chain C against the predicted model Q8IUH5: TM-score 0.98, RMSD 0.97 Å
Elsewhere
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