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UniProt Q8IUD6

E3 ubiquitin-protein ligase RNF135 (Q8IUD6)

E3 ubiquitin-protein ligase RNF135 (UniProt Q8IUD6), EC 2.3.2.27: 7 experimental structures on GenesisL1, 27 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
Q8IUD6
Protein
E3 ubiquitin-protein ligase RNF135
EC
2.3.2.27
Experimental structures
7
Predicted models
0
Pockets
27 · 4 records with a druggable one

Structures

7 records of Q8IUD6 in the MolNFT archive: 7 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
7JL1Cryo-EM structure of RIG-I:dsRNA in complex with RIPLET PrySpry domain (monomer)electron microscopyB—3 (best 0.71)
7JL1Cryo-EM structure of rig-I:DSRNA in complex with riplet pryspry domain (monomer)electron microscopyB——
7JL3Cryo-EM structure of rig-I:DSRNA filament in complex with riplet pryspry domain (trimer)electron microscopyB, D, F——
8G7TCryo-EM structure of Riplet:RIG-I:dsRNA complex (end-end)electron microscopyB, D—8 (best 0.77)
8G7UCryo-EM structure of Riplet:RIG-I:dsRNA complex (end-semi-closed end)electron microscopyB, D—7 (best 0.83)
8G7VCryo-EM structure of Riplet:RIG-I:dsRNA complex (end-inter)electron microscopyB, D—9 (best 0.74)
Q8IUD6AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase RNF135 (Q8IUD6)———

Elsewhere

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