UniProt Q8ILW9
Actin-2 (Q8ILW9)
Actin-2 (UniProt Q8ILW9), EC 3.6.4.-: 2 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 40 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8ILW9
- Protein
- Actin-2
- EC
- 3.6.4.-
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 40 · 2 records with a druggable one
Structures
3 records of Q8ILW9 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8CCN | Filamentous actin II from Plasmodium falciparum | electron microscopy | A, B, C, D, E, F | ADP, MG | 20 (best 0.80) |
| 8CCO | JAS-stabilized F-ActinII from Plasmodium falciparum | electron microscopy | A, B, C, D, E, F | 9UE, ADP, MG | 20 (best 0.80) |
| Q8ILW9 | AlphaFold monomer V2.0 prediction for actin-2 (Q8ILW9) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8CCN chain C against the predicted model Q8ILW9: TM-score 0.96, RMSD 1.47 Å
- 8CCN chain E against the predicted model Q8ILW9: TM-score 0.96, RMSD 1.47 Å
- 8CCN chain D against the predicted model Q8ILW9: TM-score 0.96, RMSD 1.47 Å
- 8CCN chain B against the predicted model Q8ILW9: TM-score 0.96, RMSD 1.47 Å
- 8CCN chain F against the predicted model Q8ILW9: TM-score 0.96, RMSD 1.47 Å
- 8CCN chain A against the predicted model Q8ILW9: TM-score 0.96, RMSD 1.47 Å
- 8CCO chain E against the predicted model Q8ILW9: TM-score 0.96, RMSD 1.49 Å
- 8CCO chain B against the predicted model Q8ILW9: TM-score 0.96, RMSD 1.49 Å
- 8CCO chain D against the predicted model Q8ILW9: TM-score 0.96, RMSD 1.49 Å
- 8CCO chain C against the predicted model Q8ILW9: TM-score 0.96, RMSD 1.49 Å
Elsewhere
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