UniProt Q8IFM5
Reticulocyte-binding protein homolog 5 (Q8IFM5)
Reticulocyte-binding protein homolog 5 (UniProt Q8IFM5): 11 experimental structures and 1 predicted model on GenesisL1, 90 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8IFM5
- Protein
- Reticulocyte-binding protein homolog 5
- Experimental structures
- 11
- Predicted models
- 1
- Pockets
- 90 · 9 records with a druggable one
Structures
12 records of Q8IFM5 in the MolNFT archive: 11 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6RCU | PfRH5 bound to monoclonal antibodies R5.004 and R5.016 | x-ray diffraction | A | — | 8 (best 0.65) |
| 6RCU | PFRH5 bound to monoclonal antibodies R5.004 and R5.016 | x-ray diffraction | A | — | — |
| 6RCV | PfRH5 bound to monoclonal antibodies R5.011 and R5.016 | x-ray diffraction | A, F | — | 14 (best 0.60) |
| 6RCV | PFRH5 bound to monoclonal antibodies R5.011 and R5.016 | x-ray diffraction | A, F | — | — |
| 7PHU | PfRH5 bound to monoclonal antibody R5.015 and R5.016 Fab fragments | x-ray diffraction | A | — | 7 (best 0.55) |
| 7PHU | PFRH5 bound to monoclonal antibody R5.015 and R5.016 Fab fragments | x-ray diffraction | A | — | — |
| 8CDD | PfRH5-PfCyRPA-PfRIPR complex from Plasmodium falciparum bound to antibody Cy.003 | electron microscopy | C | — | 8 (best 0.77) |
| 8PWU | PfRH5 bound to monoclonal antibody MAD10-255 | x-ray diffraction | A, C, E, G, I, K | — | 20 (best 0.83) |
| 8PWW | PfRH5 bound to monoclonal antibody MAD8-151 | x-ray diffraction | A, C | — | 9 (best 0.65) |
| 8PWX | PfRH5 bound to monoclonal antibody R5.008 | x-ray diffraction | B | — | 5 (best 0.73) |
| 8Q5D | PfRH5 bound to monoclonal antibody MAD10-466 | x-ray diffraction | A, D | — | 7 (best 0.77) |
| Q8IFM5 | AlphaFold monomer V2.0 prediction for reticulocyte-binding protein homolog 5 (Q8IFM5) | predicted | A | — | 12 (best 0.68) |
Experiment against prediction
- 8Q5D chain D against the predicted model Q8IFM5: TM-score 0.99, RMSD 0.54 Å
- 8Q5D chain A against the predicted model Q8IFM5: TM-score 0.98, RMSD 1.06 Å
- 8PWW chain C against the predicted model Q8IFM5: TM-score 0.98, RMSD 1.13 Å
- 6RCV chain F against the predicted model Q8IFM5: TM-score 0.97, RMSD 1.21 Å
- 6RCV chain F against the predicted model Q8IFM5: TM-score 0.97, RMSD 1.21 Å
- 8PWX chain B against the predicted model Q8IFM5: TM-score 0.97, RMSD 1.40 Å
- 8PWU chain I against the predicted model Q8IFM5: TM-score 0.97, RMSD 1.44 Å
- 8PWU chain K against the predicted model Q8IFM5: TM-score 0.97, RMSD 1.48 Å
- 6RCV chain A against the predicted model Q8IFM5: TM-score 0.97, RMSD 1.37 Å
- 6RCV chain A against the predicted model Q8IFM5: TM-score 0.97, RMSD 1.37 Å
Elsewhere
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