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UniProt Q8I6U4

Cysteine proteinase falcipain 2a (Q8I6U4)

Cysteine proteinase falcipain 2a (UniProt Q8I6U4), EC 3.4.22.-: 6 experimental structures on GenesisL1, 4 ligands bound, 22 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
Q8I6U4
Protein
Cysteine proteinase falcipain 2a
EC
3.4.22.-
Experimental structures
6
Predicted models
0
Ligands
4
Pockets
22 · 3 records with a druggable one

Structures

6 records of Q8I6U4 in the MolNFT archive: 6 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
6JW9Crystal structure of E-64 inhibited falcipain 2 from Plasmodium falciparum, strain 3D7x-ray diffractionA, BE64—
6JW9Crystal structure of E-64 inhibited falcipain 2 from plasmodium falciparum, strain 3D7x-ray diffractionA, BE64—
7EI0Crystal structure of falcipain 2 from 3D7 strainx-ray diffractionA, BSO4, NA, CL3 (best 0.77)
7EI0Crystal structure of falcipain 2 from 3D7 strainx-ray diffractionA, BSO4, NA, CL—
8GT0Structure of falcipain and human Stefin A complexx-ray diffractionA, C, ENA8 (best 0.76)
8GT7Structure of falcipain and human Stefin A mutant complexx-ray diffractionA, CNA, SO411 (best 0.79)

Ligands

  • NA · Sodium ion · in 4 records
  • SO4 · Sulfate ion · in 3 records
  • CL · Chloride ion · in 2 records
  • E64 · N-[N-[1-hydroxycarboxyethyl-carbonyl]leucylamino-butyl]-guanidine · in 2 records

Elsewhere

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