UniProt Q8GXJ1
Histone deacetylase 15 (Q8GXJ1)
Histone deacetylase 15 (UniProt Q8GXJ1), EC 3.5.1.98: 2 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 13 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8GXJ1
- Protein
- Histone deacetylase 15
- EC
- 3.5.1.98
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 13 · 2 records with a druggable one
Structures
3 records of Q8GXJ1 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6J6T | Crystal Structure of HDA15 HD domain | x-ray diffraction | A, B, C, D | ZN, K, SO4 | 8 (best 0.80) |
| 6J6T | Crystal structure of HDA15 hd domain | x-ray diffraction | A, B, C, D | ZN, K, SO4 | — |
| Q8GXJ1 | AlphaFold monomer V2.0 prediction for histone deacetylase 15 (Q8GXJ1) | predicted | A | — | 5 (best 0.58) |
Ligands
Experiment against prediction
- 6J6T chain D against the predicted model Q8GXJ1: TM-score 1.00, RMSD 0.43 Å
- 6J6T chain D against the predicted model Q8GXJ1: TM-score 1.00, RMSD 0.43 Å
- 6J6T chain C against the predicted model Q8GXJ1: TM-score 1.00, RMSD 0.46 Å
- 6J6T chain C against the predicted model Q8GXJ1: TM-score 1.00, RMSD 0.46 Å
- 6J6T chain A against the predicted model Q8GXJ1: TM-score 1.00, RMSD 0.47 Å
- 6J6T chain A against the predicted model Q8GXJ1: TM-score 1.00, RMSD 0.47 Å
- 6J6T chain B against the predicted model Q8GXJ1: TM-score 0.99, RMSD 0.64 Å
- 6J6T chain B against the predicted model Q8GXJ1: TM-score 0.99, RMSD 0.64 Å
Elsewhere
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