UniProt Q8EVR5
Cytosine-specific methyltransferase (Q8EVR5)
Cytosine-specific methyltransferase (UniProt Q8EVR5): 6 experimental structures on GenesisL1, 4 ligands bound, 19 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q8EVR5
- Protein
- Cytosine-specific methyltransferase
- Experimental structures
- 6
- Predicted models
- 0
- Ligands
- 4
- Pockets
- 19 · 4 records with a druggable one
Structures
6 records of Q8EVR5 in the MolNFT archive: 6 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4DKJ | CpG specific methyltransferase in complex with target DNA | x-ray diffraction | A | — | — |
| 4DKJ | Cpg specific methyltransferase in complex with target DNA | x-ray diffraction | A | — | — |
| 8C56 | CpG specific M.MpeI methyltransferase crystallized in the presence of 2'-deoxy-5-methylzebularine… | x-ray diffraction | A | SAH | 7 (best 0.77) |
| 8C57 | CpG specific M.MpeI methyltransferase crystallized in the presence of 5,6-dihydro-5-azacytosine… | x-ray diffraction | A | SAM, CO3 | 4 (best 0.77) |
| 8C58 | CpG specific M.MpeI methyltransferase crystallized in the presence of 5-hydroxycytosine and… | x-ray diffraction | A | SAM, CO3 | 4 (best 0.78) |
| 8C59 | CpG specific M.MpeI methyltransferase crystallized in the presence of 5-bromocytosine (converted to… | x-ray diffraction | A | SAM, NA, CO3 | 4 (best 0.77) |
Ligands
Elsewhere
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