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UniProt Q8EBR3

2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (Q8EBR3)

2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (UniProt Q8EBR3), EC 4.6.1.12: 2 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 8 pockets. Binding sites, druggability and experiment against…

UniProt
Q8EBR3
Protein
2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
EC
4.6.1.12
Experimental structures
2
Predicted models
1
Ligands
3
Pockets
8 · 2 records with a druggable one

Structures

3 records of Q8EBR3 in the MolNFT archive: 2 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
1T0ACrystal Structure of 2C-Methyl-D-Erythritol-2,4-cyclodiphosphate Synthase from Shewanella Oneidensisx-ray diffractionA, B, CZN, CO, FPP4 (best 0.85)
1T0ACrystal structure of 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase from shewanella oneidensisx-ray diffractionA, B, CZN, CO, FPP4 (best 0.85)
Q8EBR3AlphaFold monomer V2.0 prediction for 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (Q8EBR3)predictedA——

Ligands

  • CO · Cobalt (II) ion · in 2 records
  • FPP · Farnesyl diphosphate · in 2 records
  • ZN · Zinc ion · in 2 records

Experiment against prediction

Elsewhere

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