UniProt Q8CJ12
Adhesion G-protein coupled receptor G2 (Q8CJ12)
Adhesion G-protein coupled receptor G2 (UniProt Q8CJ12): 12 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 26 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8CJ12
- Protein
- Adhesion G-protein coupled receptor G2
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 26 · 6 records with a druggable one
Structures
13 records of Q8CJ12 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7WUI | Tethered peptide activation mechanism of adhesion GPCRs ADGRG2 and ADGRG4 | electron microscopy | R | — | 3 (best 0.80) |
| 7WUI | Tethered peptide activation mechanism of adhesion gpcrs ADGRG2 and ADGRG4 | electron microscopy | R | — | — |
| 7WUQ | Tethered peptide activation mechanism of adhesion GPCRs ADGRG2 and ADGRG4 | electron microscopy | R | — | 5 (best 0.82) |
| 7WUQ | Tethered peptide activation mechanism of adhesion gpcrs ADGRG2 and ADGRG4 | electron microscopy | R | — | — |
| 7XKD | Cryo-EM structure of DHEA-ADGRG2-BT-Gs complex | electron microscopy | R | AND | 4 (best 0.77) |
| 7XKD | Cryo-EM structure of dhea-ADGRG2-bt-gs complex | electron microscopy | R | AND | — |
| 7XKE | Cryo-EM structure of DHEA-ADGRG2-FL-Gs complex | electron microscopy | R | AND | 5 (best 0.75) |
| 7XKE | Cryo-EM structure of dhea-ADGRG2-fl-gs complex | electron microscopy | R | AND | — |
| 7XKF | Cryo-EM structure of DHEA-ADGRG2-BT-Gs complex at lower state | electron microscopy | R | AND | 4 (best 0.77) |
| 7XKF | Cryo-EM structure of dhea-ADGRG2-bt-gs complex at lower state | electron microscopy | R | AND | — |
| 7YP7 | apo-ADGRG2 coupled to Gs | electron microscopy | R | — | 5 (best 0.74) |
| 7YP7 | Apo-ADGRG2 coupled to gs | electron microscopy | R | — | — |
| Q8CJ12 | AlphaFold monomer V2.0 prediction for adhesion G-protein coupled receptor G2 (Q8CJ12) | predicted | A | — | — |
Ligands
- AND · 3-beta-hydroxy-5-androsten-17-one · in 6 records
Experiment against prediction
- 7WUI chain R against the predicted model Q8CJ12: TM-score 0.91, RMSD 1.99 Å
- 7WUI chain R against the predicted model Q8CJ12: TM-score 0.91, RMSD 1.99 Å
- 7YP7 chain R against the predicted model Q8CJ12: TM-score 0.91, RMSD 2.06 Å
- 7YP7 chain R against the predicted model Q8CJ12: TM-score 0.91, RMSD 2.06 Å
- 7XKE chain R against the predicted model Q8CJ12: TM-score 0.90, RMSD 2.25 Å
- 7XKE chain R against the predicted model Q8CJ12: TM-score 0.90, RMSD 2.25 Å
- 7XKD chain R against the predicted model Q8CJ12: TM-score 0.89, RMSD 2.43 Å
- 7XKF chain R against the predicted model Q8CJ12: TM-score 0.89, RMSD 2.43 Å
- 7XKD chain R against the predicted model Q8CJ12: TM-score 0.89, RMSD 2.43 Å
- 7XKF chain R against the predicted model Q8CJ12: TM-score 0.89, RMSD 2.43 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.