UniProt Q8CGP6
Histone H2A type 1-H (Q8CGP6)
Histone H2A type 1-H (UniProt Q8CGP6): 3 experimental structures and 1 predicted model on GenesisL1, 11 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8CGP6
- Protein
- Histone H2A type 1-H
- Experimental structures
- 3
- Predicted models
- 1
- Pockets
- 11 · 1 record with a druggable one
Structures
4 records of Q8CGP6 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2F8N | 2.9 Angstrom X-ray structure of hybrid macroH2A nucleosomes | x-ray diffraction | K | — | — |
| 2F8N | 2.9 ångström X-ray structure of hybrid MACROH2A nucleosomes | x-ray diffraction | K | — | — |
| 8GRQ | Cryo-EM structure of BRCA1/BARD1 bound to H2AK127-UbcH5c-Ub nucleosome | electron microscopy | C, G | — | 11 (best 0.78) |
| Q8CGP6 | AlphaFold monomer V2.0 prediction for histone H2A type 1-H (Q8CGP6) | predicted | A | — | — |
Experiment against prediction
- 2F8N chain K against the predicted model Q8CGP6: TM-score 0.96, RMSD 0.75 Å
- 2F8N chain K against the predicted model Q8CGP6: TM-score 0.96, RMSD 0.75 Å
- 8GRQ chain G against the predicted model Q8CGP6: TM-score 0.93, RMSD 1.32 Å
- 8GRQ chain C against the predicted model Q8CGP6: TM-score 0.93, RMSD 1.35 Å
Elsewhere
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