UniProt Q8CFI0
E3 ubiquitin-protein ligase NEDD4-like (Q8CFI0)
E3 ubiquitin-protein ligase NEDD4-like (UniProt Q8CFI0): 6 experimental structures and 1 predicted model on GenesisL1, 9 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8CFI0
- Protein
- E3 ubiquitin-protein ligase NEDD4-like
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 9 · 1 record with a druggable one
Structures
7 records of Q8CFI0 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1WR3 | Solution structure of the first WW domain of Nedd4-2 | solution nmr | A | — | — |
| 1WR3 | Solution structure of the first ww domain of NEDD4-2 | solution nmr | A | — | — |
| 1WR4 | Solution structure of the second WW domain of Nedd4-2 | solution nmr | A | — | — |
| 1WR4 | Solution structure of the second ww domain of NEDD4-2 | solution nmr | A | — | — |
| 1WR7 | Solution structure of the third WW domain of Nedd4-2 | solution nmr | A | — | — |
| 1WR7 | Solution structure of the third ww domain of NEDD4-2 | solution nmr | A | — | — |
| Q8CFI0 | AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase NEDD4-like (Q8CFI0) | predicted | A | — | 9 (best 0.73) |
Experiment against prediction
- 1WR4 chain A against the predicted model Q8CFI0: TM-score 0.74, RMSD 1.37 Å
- 1WR4 chain A against the predicted model Q8CFI0: TM-score 0.74, RMSD 1.37 Å
- 1WR7 chain A against the predicted model Q8CFI0: TM-score 0.70, RMSD 1.85 Å
- 1WR7 chain A against the predicted model Q8CFI0: TM-score 0.70, RMSD 1.85 Å
- 1WR3 chain A against the predicted model Q8CFI0: TM-score 0.65, RMSD 1.47 Å
- 1WR3 chain A against the predicted model Q8CFI0: TM-score 0.65, RMSD 1.47 Å
Elsewhere
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