UniProt Q8CDI2

F-box only protein 43 (Q8CDI2)

F-box only protein 43 (UniProt Q8CDI2): 6 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt: Q8CDI2
Protein: F-box only protein 43
Experimental structures: 6
Predicted models: 1
Ligands: 1

Structures

7 records of Q8CDI2 in the MolNFT archive: 6 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
2RT9	Solution structure of a regulatory domain of meiosis inhibitor	solution nmr	A	ZN	—
2RT9	Solution structure of a regulatory domain of meiosis inhibitor	solution nmr	A	ZN	—
5DMS	Mouse Polo-box domain and Emi2 (169-177)	x-ray diffraction	B, D	—	—
5DMS	Mouse polo-box domain and EMI2 (169-177)	x-ray diffraction	B, D	—	—
5DMV	Polo-box domain of Mouse Polo-like kinase 1 complexed with Emi2 (146-177)	x-ray diffraction	D	—	—
5DMV	Polo-box domain of mouse polo-like kinase 1 complexed with EMI2 (146- 177)	x-ray diffraction	D	—	—
Q8CDI2	AlphaFold monomer V2.0 prediction for F-box only protein 43 (Q8CDI2)	predicted	A	—	—

Ligands

ZN · Zinc ion · in 2 records

Experiment against prediction

2RT9 chain A against the predicted model Q8CDI2: TM-score 0.78, RMSD 1.90 Å
2RT9 chain A against the predicted model Q8CDI2: TM-score 0.78, RMSD 1.90 Å
5DMS chain D against the predicted model Q8CDI2: TM-score 0.56, RMSD 1.10 Å
5DMS chain D against the predicted model Q8CDI2: TM-score 0.56, RMSD 1.10 Å
5DMS chain B against the predicted model Q8CDI2: TM-score 0.43, RMSD 0.77 Å
5DMS chain B against the predicted model Q8CDI2: TM-score 0.43, RMSD 0.77 Å
5DMV chain D against the predicted model Q8CDI2: TM-score 0.25, RMSD 2.29 Å
5DMV chain D against the predicted model Q8CDI2: TM-score 0.25, RMSD 2.29 Å

Elsewhere

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