UniProt Q86XP3
ATP-dependent RNA helicase DDX42 (Q86XP3)
ATP-dependent RNA helicase DDX42 (UniProt Q86XP3), EC 3.6.4.13: 4 experimental structures and 1 predicted model on GenesisL1, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q86XP3
- Protein
- ATP-dependent RNA helicase DDX42
- EC
- 3.6.4.13
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 3 · 1 record with a druggable one
Structures
5 records of Q86XP3 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7EVN | The cryo-EM structure of the DDX42-SF3b complex | electron microscopy | E | — | — |
| 7EVN | The cryo-EM structure of the DDX42-SF3B complex | electron microscopy | E | — | — |
| 8DPE | Crystal structure of ATP-dependent RNA helicase DDX42 | x-ray diffraction | A | — | — |
| 8HK1 | The cryo-EM structure of human pre-17S U2 snRNP | electron microscopy | E | — | 3 (best 0.82) |
| Q86XP3 | AlphaFold monomer V2.0 prediction for ATP-dependent RNA helicase DDX42 (Q86XP3) | predicted | A | — | — |
Experiment against prediction
- 8DPE chain A against the predicted model Q86XP3: TM-score 0.61, RMSD 2.52 Å
- 7EVN chain E against the predicted model Q86XP3: TM-score 0.54, RMSD 2.46 Å
- 7EVN chain E against the predicted model Q86XP3: TM-score 0.54, RMSD 2.46 Å
- 8HK1 chain E against the predicted model Q86XP3: TM-score 0.38, RMSD 3.58 Å
Elsewhere
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