UniProt Q86XE5
4-hydroxy-2-oxoglutarate aldolase, mitochondrial (Q86XE5)
4-hydroxy-2-oxoglutarate aldolase, mitochondrial (UniProt Q86XE5), EC 4.1.3.16: 4 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 4 pockets. Binding sites, druggability and experiment against…
- UniProt
- Q86XE5
- Protein
- 4-hydroxy-2-oxoglutarate aldolase, mitochondrial
- EC
- 4.1.3.16
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 4 · 4 records with a druggable one
Structures
5 records of Q86XE5 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3S5N | Crystal Structure of Human 4-hydroxy-2-oxoglutarate Aldolase | x-ray diffraction | A | K, NA | 1 (best 0.57) |
| 3S5N | Crystal structure of human 4-hydroxy-2-oxoglutarate aldolase | x-ray diffraction | A | K, NA | 1 (best 0.57) |
| 3S5O | Crystal Structure of Human 4-hydroxy-2-oxoglutarate Aldolase Bound to Pyruvate | x-ray diffraction | A | K | 1 (best 0.56) |
| 3S5O | Crystal structure of human 4-hydroxy-2-oxoglutarate aldolase bound to pyruvate | x-ray diffraction | A | K | 1 (best 0.56) |
| Q86XE5 | AlphaFold monomer V2.0 prediction for 4-hydroxy-2-oxoglutarate aldolase, mitochondrial (Q86XE5) | predicted | A | — | — |
Ligands
Experiment against prediction
- 3S5O chain A against the predicted model Q86XE5: TM-score 1.00, RMSD 0.17 Å
- 3S5O chain A against the predicted model Q86XE5: TM-score 1.00, RMSD 0.17 Å
- 3S5N chain A against the predicted model Q86XE5: TM-score 1.00, RMSD 0.20 Å
- 3S5N chain A against the predicted model Q86XE5: TM-score 1.00, RMSD 0.20 Å
Elsewhere
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