UniProt Q86WJ1
Chromodomain-helicase-DNA-binding protein 1-like (Q86WJ1)
Chromodomain-helicase-DNA-binding protein 1-like (UniProt Q86WJ1), EC 3.6.4.12: 7 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 6 pockets. Binding sites, druggability and experiment against…
- UniProt
- Q86WJ1
- Protein
- Chromodomain-helicase-DNA-binding protein 1-like
- EC
- 3.6.4.12
- Experimental structures
- 7
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 6 · 1 record with a druggable one
Structures
8 records of Q86WJ1 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6ZHX | Cryo-EM structure of the regulatory linker of ALC1 bound to the NUCLEOSOME'S acidic patch… | electron microscopy | K, L | — | — |
| 6ZHY | Cryo-EM structure of the regulatory linker of ALC1 bound to the NUCLEOSOME'S acidic patch: hexasome… | electron microscopy | K | — | — |
| 7ENN | The structure of ALC1 bound to the nucleosome | electron microscopy | K | ADP, BEF | — |
| 7ENN | The structure of ALC1 bound to the nucleosome | electron microscopy | K | ADP, BEF | — |
| 7EPU | Crystal structure of HSALC1 | x-ray diffraction | B | ADP, MG | — |
| 7OTQ | Cryo-EM structure of ALC1/CHD1L bound to a parylated nucleosome | electron microscopy | K | — | — |
| 8B0A | Cryo-EM structure of ALC1 bound to an asymmetric, site-specifically PARylated nucleosome | electron microscopy | K | — | 6 (best 0.86) |
| Q86WJ1 | AlphaFold monomer V2.0 prediction for chromodomain-helicase-DNA- binding protein 1-like (Q86WJ1) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6ZHY chain K against the predicted model Q86WJ1: TM-score 0.94, RMSD 0.13 Å
- 8B0A chain K against the predicted model Q86WJ1: TM-score 0.91, RMSD 2.18 Å
- 6ZHX chain L against the predicted model Q86WJ1: TM-score 0.91, RMSD 0.16 Å
- 7ENN chain K against the predicted model Q86WJ1: TM-score 0.91, RMSD 2.45 Å
- 7ENN chain K against the predicted model Q86WJ1: TM-score 0.91, RMSD 2.45 Å
- 7OTQ chain K against the predicted model Q86WJ1: TM-score 0.90, RMSD 2.30 Å
- 6ZHX chain K against the predicted model Q86WJ1: TM-score 0.84, RMSD 0.22 Å
- 7EPU chain B against the predicted model Q86WJ1: TM-score 0.53, RMSD 6.59 Å
Elsewhere
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