UniProt Q86W24
Nacht, lrr and pyd domains-containing protein 14 (Q86W24)
Nacht, lrr and pyd domains-containing protein 14 (UniProt Q86W24): 6 experimental structures and 1 predicted model on GenesisL1, 11 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q86W24
- Protein
- Nacht, lrr and pyd domains-containing protein 14
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 11 · 1 record with a druggable one
Structures
7 records of Q86W24 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4N1J | Crystal structures of NLRP14 pyrin domain reveal a conformational switch mechanism, regulating its… | x-ray diffraction | A, B, C, D | — | — |
| 4N1J | Crystal structures of NLRP14 pyrin domain reveal a conformational switch mechanism, regulating its… | x-ray diffraction | A, B, C, D | — | — |
| 4N1K | Crystal structures of NLRP14 pyrin domain reveal a conformational switch mechanism, regulating its… | x-ray diffraction | A, B, C, D | — | — |
| 4N1K | Crystal structures of NLRP14 pyrin domain reveal a conformational switch mechanism, regulating its… | x-ray diffraction | A, B, C, D | — | — |
| 4N1L | Crystal structures of NLRP14 pyrin domain reveal a conformational switch mechanism, regulating its… | x-ray diffraction | A | — | — |
| 4N1L | Crystal structures of NLRP14 pyrin domain reveal a conformational switch mechanism, regulating its… | x-ray diffraction | A | — | — |
| Q86W24 | AlphaFold monomer V2.0 prediction for nacht, lrr and pyd domains- containing protein 14 (Q86W24) | predicted | A | — | 11 (best 0.77) |
Experiment against prediction
- 4N1L chain A against the predicted model Q86W24: TM-score 0.86, RMSD 1.74 Å
- 4N1L chain A against the predicted model Q86W24: TM-score 0.86, RMSD 1.74 Å
- 4N1K chain C against the predicted model Q86W24: TM-score 0.77, RMSD 2.29 Å
- 4N1K chain C against the predicted model Q86W24: TM-score 0.77, RMSD 2.29 Å
- 4N1J chain D against the predicted model Q86W24: TM-score 0.77, RMSD 2.29 Å
- 4N1J chain D against the predicted model Q86W24: TM-score 0.77, RMSD 2.29 Å
- 4N1K chain A against the predicted model Q86W24: TM-score 0.76, RMSD 2.46 Å
- 4N1K chain A against the predicted model Q86W24: TM-score 0.76, RMSD 2.46 Å
- 4N1K chain D against the predicted model Q86W24: TM-score 0.76, RMSD 2.42 Å
- 4N1K chain D against the predicted model Q86W24: TM-score 0.76, RMSD 2.42 Å
Elsewhere
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