UniProt Q86VP6
Cullin-associated NEDD8-dissociated protein 1 (Q86VP6)
Cullin-associated NEDD8-dissociated protein 1 (UniProt Q86VP6): 16 experimental structures and 1 predicted model on GenesisL1, 136 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q86VP6
- Protein
- Cullin-associated NEDD8-dissociated protein 1
- Experimental structures
- 16
- Predicted models
- 1
- Pockets
- 136 · 12 records with a druggable one
Structures
17 records of Q86VP6 in the MolNFT archive: 16 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1U6G | Crystal Structure of The Cand1-Cul1-Roc1 Complex | x-ray diffraction | C | — | — |
| 1U6G | Crystal structure of the CAND1-CUL1-ROC1 complex | x-ray diffraction | C | — | — |
| 4A0C | Structure of the CAND1-CUL4B-RBX1 complex | x-ray diffraction | A, B | — | — |
| 4A0C | Structure of the CAND1-CUL4B-RBX1 complex | x-ray diffraction | A, B | — | — |
| 7Z8R | CAND1-CUL1-RBX1 | electron microscopy | D | — | 15 (best 0.85) |
| 7Z8T | CAND1-SCF-SKP2 CAND1 engaged SCF rocked | electron microscopy | D | — | 10 (best 0.85) |
| 7Z8V | CAND1-SCF-SKP2 (SKP1deldel) CAND1 engaged SCF rocked | electron microscopy | D | — | 10 (best 0.85) |
| 7ZBW | CAND1-SCF-SKP2 CAND1 rolling-2 SCF engaged | electron microscopy | D | — | 9 (best 0.75) |
| 7ZBZ | CAND1 delhairpin-SCF-SKP2 CAND1 partly engaged SCF partly rocked | electron microscopy | D | — | 10 (best 0.86) |
| 8CDJ | CAND1 b-hairpin++-SCF-SKP2 CAND1 rolling SCF engaged | electron microscopy | D | — | 11 (best 0.72) |
| 8CDK | CAND1 b-hairpin++-SCF-SKP2 CAND1 partly engaged SCF partly rocked | electron microscopy | D | — | 9 (best 0.84) |
| 8H3Q | Cryo-EM Structure of the CAND1-Cul3-Rbx1 complex | electron microscopy | A | — | 13 (best 0.85) |
| 8OR0 | CAND1-CUL1-RBX1-SKP1-SKP2-CKS1-CDK2 | electron microscopy | C | — | 11 (best 0.86) |
| 8OR2 | CAND1-CUL1-RBX1-DCNL1 | electron microscopy | C | — | 14 (best 0.87) |
| 8OR3 | CAND1-CUL1-RBX1-SKP1-SKP2-DCNL1 | electron microscopy | C | — | 12 (best 0.85) |
| 8OR4 | Partially dissociated CAND1-CUL1-RBX1-SKP1-SKP2-CKS1-CDK2 | electron microscopy | C | — | 12 (best 0.83) |
| Q86VP6 | AlphaFold monomer V2.0 prediction for cullin-associated NEDD8-dissociated protein 1 (Q86VP6) | predicted | A | — | — |
Experiment against prediction
- 8CDJ chain D against the predicted model Q86VP6: TM-score 0.89, RMSD 3.53 Å
- 7ZBW chain D against the predicted model Q86VP6: TM-score 0.89, RMSD 3.59 Å
- 8OR4 chain C against the predicted model Q86VP6: TM-score 0.86, RMSD 3.77 Å
- 8OR0 chain C against the predicted model Q86VP6: TM-score 0.86, RMSD 4.79 Å
- 1U6G chain C against the predicted model Q86VP6: TM-score 0.85, RMSD 4.47 Å
- 1U6G chain C against the predicted model Q86VP6: TM-score 0.85, RMSD 4.47 Å
- 8CDK chain D against the predicted model Q86VP6: TM-score 0.84, RMSD 4.72 Å
- 7ZBZ chain D against the predicted model Q86VP6: TM-score 0.84, RMSD 4.77 Å
- 7Z8R chain D against the predicted model Q86VP6: TM-score 0.84, RMSD 4.71 Å
- 7Z8T chain D against the predicted model Q86VP6: TM-score 0.84, RMSD 4.81 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.